Protein Alignment Gbf1 and garz

DIOPT Version :9

• Sequence 1: XP_006231558.1
• Gene: Gbf1 / 309451
• RGDID: 1307160
• Length: 1895
• Species: Rattus norvegicus
• Sequence 2: NP_610761.2
• Gene: garz / 36337
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Alignment Length: 1963
• Identity: 829/1963 - (42%)
• Similarity: 1128/1963 - (57%)
• Gaps: 278/1963 - (14%)

  Rat     6 IYIIQGEINIVVGAIKRNARWSTHIPLDEERDPLLHSFSHLKEVLNSGTELSEIEPNVFLRPFLE 70
            ||:::||:..::.|::|..||:....:|:|.|.||..|..||..||...:|.:|||.|||.||||
  Fly     8 IYVVRGEMATLMTAMRRGTRWNATAYVDDENDSLLKLFIDLKHELNRIEDLRQIEPQVFLAPFLE 72

  Rat    71 VIRSEDTTGPITGLALTSVNKFLSCALIDPTHEGTAEGMENMADAVTHARFVGTDPASDEVVLMK 135
            |||:.|.|||:|.|||.||||.||..|||||....|:.:|.:|||||||||:|||.:||.|..|:
  Fly    73 VIRTADATGPLTSLALASVNKLLSYGLIDPTSPNLADIVERIADAVTHARFMGTDQSSDGVTFMR 137

  Rat   136 ILQVLRTLLLTPVGTHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFK 200
            :::||.||:.:|.|..::|.|:||:|.|||:|.||.|||||||:|||.:|.|||.|.|.|||||.
  Fly   138 VIEVLHTLIRSPEGAAVSNVSMCEVMLSCFKISFEPRLSELLRRSAEKSLKDMVLLFFMRLPQFA 202

  Rat   201 EEPKSYVGTNLKKISPCLLNTLELSSGEQTKALNQLERVLLFKNLKLKMRAGGMSDSSKWKKQKR 265
            ||...   |.|:|         ..:.|:......|       :.||.|..|...:...|....:.
  Fly   203 EERSD---TMLQK---------RFTIGDAASGATQ-------EKLKRKTVAQAQTAPRKSSAVEE 248

  Rat   266 SPRPPRHTTKVMPGSELPTPNGAALSSNLTGGMPFIEAPTSISSASSEAASTVVSPCTDSGLELS 330
            .|:.|:.....:||                    .::||.        .|:|..||   :|..|.
  Fly   249 PPQTPQSANLTVPG--------------------HLKAPI--------LATTPASP---AGNILD 282

  Rat   331 SQATSKEDLTDLEQAGSPREITTTEPGSTEIGVSDQLDPQQEGAHVEKAQSASVESIPEVLEECT 395
            .|.                :||.|...:...|..:...|:.....||     |.||.|.:..|..
  Fly   283 MQG----------------KITQTPTTTASTGEDETTVPETPVIQVE-----STESEPLLDGETG 326

  Rat   396 SPTDHSDSASVHDMDYVNPRGVRFT-QSSQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEV 459
            ..|  |..|..:..:|:|..||||| ||:..:.|:|.|||||.|:|||||||.|.||.|:.||:.
  Fly   327 EAT--STLAEANSSEYINSVGVRFTQQSTDHDVTSLSPYGLPFIQELFRFLIILCNPLDKQNSDS 389

  Rat   460 MIHMGLHLLTVALESAP--VAQCQTLLGLIKDEMCRHLFQLLSVERLNLYAASLRVCFLLFESMR 522
            |:|.||.|||||.|.|.  :.:.:.||.|:||::||:|..|||.|||:::||.|::|||||||:|
  Fly   390 MMHTGLSLLTVAFEVAADNIGKYEGLLELVKDDLCRNLISLLSSERLSIFAADLQLCFLLFESLR 454

  Rat   523 EHLKFQLEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFE 587
            .|||||||.|::||.|||..:|||.||||:|:||:.::||||||.||||||||||||.||:::||
  Fly   455 GHLKFQLEAYLRKLSEIIASDNPKTPYEMRELALDNLLQLWRIPGFVTELYINYDCDLYCTDMFE 519

  Rat   588 DLTKLLSKNAFPVSGQLYTTHLLSLDALLTVIDSTEAHCQAKVLNTLNQQEKKETARPGFEAVDG 652
            .||.||||.....:..:|:||::|:|.||:||||.|.:|.|. .|:.|.:|....|.|   |..|
  Fly   520 SLTNLLSKYTLSATNAVYSTHIISMDTLLSVIDSIERNCAAS-KNSSNNRESLPEAAP---ATGG 580

  Rat   653 SPDTYKSERAASDGKATGVPSDAPGLHFSSGGWLSTEHGKPGCSDLEEA---------GDSGVDK 708
            |..:..:             |...|:...||..::.|......:....|         |..||..
  Fly   581 SRHSRHN-------------SGLEGIVIDSGNSVAAEEKVENIASFINASSHRLRLQSGGEGVGI 632

  Rat   709 KTTRKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQW 773
            .:              .:|.::|.||:||..|||:|||:|:||||:|||.|:|...:|..:||.:
  Fly   633 TS--------------EQLAKVKQKKRLLSQGTERFNQRPEKGIQYLQEHGILNAELDPMQVALF 683

  Rat   774 LRENPRLDKKMIGEFVSDRKNMD--LLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIHRLL 836
            |||||.||||||||::|.:||:|  :|.:||.:|.|.|||:|:|||||||.||||||||:|..:|
  Fly   684 LRENPGLDKKMIGEYISKKKNVDSKILINFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIFLVL 748

  Rat   837 EVFTEHWRSCNGSPFANSDACFALAYAVIMLNTDQHNHNVRKQNAPMTLEEFRKNLKGVNGGKDF 901
            |.|::||...|..||||.||.|.||||:||||.||||.|.::.|.|||||:|.|||:|:|||:||
  Fly   749 EHFSDHWHKQNQDPFANVDAAFRLAYAIIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGLNGGEDF 813

  Rat   902 EQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWSVLLHRGATPEGIFLRVPPGSYDLDLFTMTWG 966
            :|::|..:::||||||||||.||||||||||.|.|||.||.|.:|.|..|...|||:::|.:.||
  Fly   814 DQEMLAQVFNAIKNEEIVMPAEQTGLVRENYQWKVLLRRGDTHDGHFHYVHDASYDVEIFNIVWG 878

  Rat   967 PTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPS 1031
            .:::|||::|||| .||..|:.::||.|.|.|||||.|...||.|:::|||||.|.|...::.|:
  Fly   879 ASLSALSFMFDKS-TETGYQRTLAGFSKSAAISAHYNLHSDFDALVLTLCKFTTLLSSVEQHEPA 942

  Rat  1032 V----------FGSNPKAHIAAKTVFHLAHRHGDILREGWKNIMEAMLQLFRAQLLPKAMVEVED 1086
            .          ||.|.||..|.:|||.|.|.:||.|||.||:|::..|||||.:||||:::||||
  Fly   943 PANNETQQAVNFGLNGKAQAAMRTVFLLVHDYGDCLRESWKHILDLYLQLFRLKLLPKSLIEVED 1007

  Rat  1087 FVDPNGKISLQREETPSNRGE----STVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVALDCIKQ 1147
            |.:.|||..|..|: |..:.|    |::.||:|        ....|.|:.|.|:..::...|||:
  Fly  1008 FCEANGKAMLILEK-PREKQESGLFSSLYSFIS--------SEGQREPTYEEQDFIKLGRKCIKE 1063

  Rat  1148 CDPEKMITESKFLQLESLQELMKALVSVTPDEE-------TYDEEDAAFCLEMLLRIVLENRDRV 1205
            |..::|:.||||:||||||||:|.::::....:       .|.|:...|.:|.|::||:.||||:
  Fly  1064 CQLDQMLQESKFVQLESLQELLKCVLALLKAPQGHKSIGLPYAEDQTVFWMEFLVKIVVHNRDRM 1128

  Rat  1206 GCVWQTVRDHLYHLCVQAQD--FCFLVERAVVGLLRLAIRLLRREEISGQVLLSLRILLLMKPSV 1268
            ..:|..|||.:|.|.:.:..  :.:|:.|.:|.:|:|||.|:|.||:...||.||::||::||::
  Fly  1129 IPLWPAVRDQMYLLLMGSASCGYDYLLNRCIVAVLKLAIYLMRNEELCPIVLQSLKMLLMLKPAL 1193

  Rat  1269 LSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPDALQATARADAPDAGAQSD 1333
            |.|:|.|::.|::|||||:|.||||..||..:|.||||:|:|..||:...|.... .|:..|:||
  Fly  1194 LLRISKQISIGIYELLKTSAQNIHSEQDWQIIFNLLECVGAGAVPPNYDDAQLPL-PPNGSAKSD 1257

  Rat  1334 SELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKMHRSATDADMANSGWLVVGKDDIDNSKPAAGLS 1398
            ..:..........:||||||||:......|.....||       ..|::|...|.:.:..:...|
  Fly  1258 GAISGEEDATAVPERGYTSDSEITKASAAPAVSSPSA-------ENWILVNNKDSELTTASRPQS 1315

  Rat  1399 RPGPS-PLVNQYSLTVGLDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASL 1462
            .|..| |.||  :|.....|..|...:|.||.:||:||||..|||||.|||.||:.:||||||..
  Fly  1316 PPSLSAPPVN--TLVYNCQLLDHAPFALFKCWDSLAFIVRSVAHITPYNFEACVRCIRIFVEACR 1378

  Rat  1463 NGGCKSQDKRGKSHKYDSKGNRFKKKPKEGSMLRRPRASSQHATRA----------GHSDEEEDE 1517
            :||.:.:.|...:.|..|...|.::||...|     .|||.:.|..          |::.|:||
  Fly  1379 DGGIRQRRKLESAAKQKSSKKRSERKPGMAS-----SASSSNLTLLTGDPSDNQINGNAAEQED- 1437

  Rat  1518 GVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETGGRKIEADSRTLWAHCWCPLL 1582
             :...|..:|:|    |||||:||:||.|.|:..||||       |..: ..|..||:..|||||
  Fly  1438 -LAQRYEQLSIQ----LLDLMYTLYTRTAQIFRWWAEE-------GCTV-PQSAALWSPGWCPLL 1489

  Rat  1583 QGIACLCCDARRQVRMQALTYL-QRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPA--- 1643
            ||||.|..|.||:||..|::.| ||||||||||.|...||.|||::||||||.:||...:.|
  Fly  1490 QGIARLAMDRRREVRTHAISCLQQRALLVHDLQTLSGTEWCSCFHQVLFPLLNELLPESNAAGQL 1554

  Rat  1644 DVGGMEETRMRASTLLSKVFLQHLSPLLSL-STFAALWLTILDFMDKYMHAGSSDLLSEAVPESL 1707
            |...:||:|:|.:|::||||||||:.|:.| :.|..|||.|||:::::|..| ||.|||.:.|.|
  Fly  1555 DAALLEESRIRTATIMSKVFLQHLTTLIELGNAFNELWLDILDYIERFMKVG-SDTLSEQMQEIL 1618

  Rat  1708 KNMLLVMDTAEIFHSADARGGSPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPTEPHSQKPL 1772
            |||||||.:..:||:.|  |....||||:||.||..|||:|::|||             |.:...
  Fly  1619 KNMLLVMHSVRVFHNQD--GSLQQALWELTWRRIGEFLPNLKEELF-------------HDEGKR 1668

  Rat  1773 ASTHLTPAAGDPRMPGHPPPPEIPSEVGACDPEKPESTRAASSSSPGSPVASSPSKQSPA----- 1832
            |.|...||                                     |.:.||::|.:|.||
  Fly  1669 AQTLTNPA-------------------------------------PQAAVAAAPQQQLPAVTILP 1696

  Rat  1833 ----------PEGPPPLAQPPLILQPLTSP-----LQVGVPPMTLPIILNPALIEATSPVPLLAT 1882
                      ...|.|.|..||:..|:.||     ||   |||...:...|:.:.|.   |::..
  Fly  1697 RQTQVSNELVVSAPTPPAATPLLGSPVESPRRSIILQ---PPMADVLQQPPSFVFAQ---PIIVP 1755

  Rat  1883 PRP---TDPIPTS 1892
            |:|   |||||.|
  Fly  1756 PQPPAVTDPIPPS 1768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gbf1	XP_006231558.1	Sec7_N	434..579	CDD:289549	92/146 (63%)
		Sec7	733..918	CDD:279680	114/186 (61%)
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	372/756 (49%)
		Sec7_N	370..512	CDD:289549	89/141 (63%)
		Sec7	643..830	CDD:279680	114/186 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342748
Domainoid	1	1.000	641	1.000	Domainoid score	I157
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37897
Inparanoid	1	1.050	1334	1.000	Inparanoid score	I133
OMA	1	1.010	-	-		QHG55524
OrthoDB	1	1.010	-	-		D49474at33208
OrthoFinder	1	1.000	-	-		FOG0003083
OrthoInspector	1	1.000	-	-		oto97810
orthoMCL	1	0.900	-	-		OOG6_102130
Panther	1	1.100	-	-	LDO	PTHR10663
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2055
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770