Protein Alignment Slc46a2 and CG8046

DIOPT Version :9

• Sequence 1: NP_066395.3
• Gene: Slc46a2 / 30936
• MGIID: 1353616
• Length: 479
• Species: Mus musculus
• Sequence 2: NP_724761.1
• Gene: CG8046 / 35936
• FlyBaseID: FBgn0033388
• Length: 519
• Species: Drosophila melanogaster
• Alignment Length: 426
• Identity: 101/426 - (23%)
• Similarity: 178/426 - (41%)
• Gaps: 66/426 - (15%)

Mouse    69 EDQQQKAISNFNIIYNLVLGLTPLLSAYGLGWLSDRYHRKISICTAMLGFLLSRIGLLLKVMLDW 133
            |:|.|...:...:...||....|.......|..:|.|.||..:..:.||:     ||...:
  Fly   118 EEQVQPYAAQVTLAMRLVECFIPAFCGLFAGSWADHYGRKPLLMCSFLGY-----GLQYLI---- 173

Mouse   134 PVEVMYGAAALNGLCGSFSAYWSGVMALGSLGC------------------SEGR-RSVRLILID 179
            ...:.|.|....||   .|.:|. |:::..|.|                  |.|: ||.|:|..:
  Fly   174 SAAIAYCAMYTQGL---VSPWWY-VLSIVPLSCLGSSVTYSVAAVCFIADVSGGKVRSYRMIAYE 234

Mouse   180 LVLGLAGFSGSMASGHLFKQIVGHSAQGLLLTACSVGCAAFALFYSLFVLKVPESKPNKVH---- 240
            |.:.:....||:.||:.::     :....::.:.|..|...|||  |..|.:|||.|.:..
  Fly   235 LAIYVGLLLGSLGSGYAYE-----ATDAYIVFSISAVCIFTALF--LMALLLPESLPARNRTLST 292

Mouse   241 PTVDT-VSGMMGTYRTLDPDQQDKQNVPRNPRTPGKGKSSQREVVALLFVGAIIYDLAAVGTVDV 304
            ||.|| |..|:.:..:.....::.||           :.....::.:|.:.|.:.|    |:..|
  Fly   293 PTTDTSVVSMLKSLWSTCSKPREHQN-----------RFMLTTIMVVLLLTAFVSD----GSNSV 342

Mouse   305 MALFVLKEPLHWNQVQLGYGMASGYIIFITSFLGVLVFSRCFRDTT------MIIIGMLSFGSGA 363
            ...| ::...||...|.......|.::...:..|.::|....|..|      :.::.:||..|.:
  Fly   343 FYKF-MRIKFHWTVKQFTEYETVGILVPAVAGSGGVLFIWSLRKCTNSAILWLALVSLLSHCSSS 406

Mouse   364 LLLAFVKETYMFYIARAIMLFALIPITTIRSAMSKLIKDSSYGKIFVILQLCLTLTGVVTSTIYN 428
            |:..|..|::..|:|..:.:|..:.....|:.::.|:.....||||.:|.:...|:.:::||:|.
  Fly   407 LMKGFALESWQIYVAIGLGVFKSLVNPMCRTMITNLLPADERGKIFALLGVLQALSPLISSTLYV 471

Mouse   429 KIYQLTLDKFIGTCFVLSSFLSFLAIVPIGVVAYKQ 464
            .||..||:...|...|.|:||..:.|:.:|.|.:|:
  Fly   472 AIYTRTLNTEPGIFNVFSAFLFGIGIILLGTVWHKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slc46a2	NP_066395.3	MFS	86..455	CDD:119392	93/398 (23%)
		MFS_1	88..422	CDD:284993	80/363 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	255..277		2/21 (10%)
CG8046	NP_724761.1	MFS_1	138..467	CDD:284993	80/364 (22%)
		MFS	141..503	CDD:119392	93/397 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844277
Domainoid	1	1.000	70	1.000	Domainoid score	I9497
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7720
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8701
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23507
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.790