DRSC/TRiP Functional Genomics Resources

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Protein Alignment Zbtb18 and CG6654

DIOPT Version :9

Sequence 1:NP_001012330.1 Gene:Zbtb18 / 30928 MGIID:1353609 Length:531 Species:Mus musculus
Sequence 2:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster


Alignment Length:548 Identity:118/548 - (21%)
Similarity:184/548 - (33%) Gaps:184/548 - (33%)


- Green bases have known domain annotations that are detailed below.


Mouse   117 DIVKVCKKKLKEKATTEADSTKKEEDASSCSDKVESLSDGSSHMAGDLPSDEDEGEDDKLNILPS 181
            |:.|:|...|                 ||....:.....||.....|:..:..:.:..:.:.||.
  Fly     2 DVDKICLTCL-----------------SSTGPLLSIYDGGSGSCLADMIREFTKTKPRRNDNLPE 49

Mouse   182 KRDLA--AEPGNMW---MRLPSDSAGIPQAGGEAEPHATAAGKTVASPCSSTESLSQ-------R 234
            |..|:  :|..|.:   ::..:.|..:.|....|.|....:..:::.|.::|:...|       |
  Fly    50 KVCLSCLSEISNCYTFKIKCENSSRTLRQLLPNALPEEPDSKVSISCPVATTDQAVQTTSWEPDR 114

Mouse   235 SVTSVRDSA--DVDCVLDLS-VKSSLSGVENLNSSYFSSQDVLRSNLVQVKVEKEASC------- 289
            ...||:..|  ..|...:.| :||::|    ::..|....:|....|....|||..|.       
  Fly   115 CTASVQTDAVTTTDAEQNTSLIKSTIS----VDLDYEGEGEVFDYELPDEPVEKTTSLILQVQGN 175

Mouse   290 --DESDV---GTN------DYDMEHS--------------------------TVKESVSTNNRVQ 317
              ||.:|   .||      |:::|..                          |.::|.:.....|
  Fly   176 LKDEKEVVFTQTNVIYEGDDHELEQQIRECNLAIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQ 240

Mouse   318 YEPAHLAPLREDSVLRELDRED-------------KASDDEMMTPESER----VQVEGGMENSL- 364
            ....|..|:......|||::|.             ....|...||.|:.    .|...|.:..| 
  Fly   241 ENDKHQTPVGSKEEARELEKEQVPQSAKRTSRRRGVVKQDVPATPPSDAEPSPKQHRLGTQRKLS 305

Mouse   365 LPYVSNILSPA--------------------------------------GQIFMCPLCNKVFPSP 391
            .|....:..|:                                      .:.:.|..|.|||.||
  Fly   306 APRAGTVNGPSTTSGAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCNECEKVFVSP 370

Mouse   392 HILQIHLSTHFRE---QDGIR--SKPAADVNV---------PTCSLCGKTFSCMYTLKRHERTHS 442
            ..|..|.::|...   :.|||  ||.|...::         ..|::|.|.|:.:.||:.|.|.|:
  Fly   371 DHLAEHQASHGAHNCPECGIRCDSKEALSKHMVQGHKRNLRNQCNICQKVFTMLSTLRDHMRIHT 435

Mouse   443 GEKPYTCTQCGKSFQYSHN----------------------------LSRHAVVHTREKPHACKW 479
            ||||:.|..|||||..:.|                            |:.||..||.:||..|:.
  Fly   436 GEKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVTKAELTSHARTHTGDKPFECEV 500

Mouse   480 CERRFTQSGDLYRHIRK------FHCEL 501
            |..|||.|..|.:|.||      :.|:|
  Fly   501 CLARFTTSCSLAKHKRKHTGERPYACDL 528

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Zbtb18NP_001012330.1 BTB_POZ_ZBTB18_RP58 10..156 CDD:349633 6/38 (16%)
COG5048 <303..>490 CDD:227381 67/310 (22%)
C2H2 Zn finger 381..401 CDD:275368 9/19 (47%)
C2H2 Zn finger 421..441 CDD:275368 8/19 (42%)
zf-H2C2_2 434..456 CDD:404364 12/21 (57%)
C2H2 Zn finger 449..469 CDD:275368 10/47 (21%)
C2H2 Zn finger 477..495 CDD:275368 8/17 (47%)
CG6654NP_650429.1 zf-AD 6..79 CDD:285071 14/89 (16%)
C2H2 Zn finger 331..354 CDD:275368 0/22 (0%)
COG5048 <357..570 CDD:227381 55/172 (32%)
C2H2 Zn finger 360..380 CDD:275368 9/19 (47%)
C2H2 Zn finger 385..406 CDD:275370 6/20 (30%)
C2H2 Zn finger 414..434 CDD:275368 8/19 (42%)
zf-H2C2_2 427..451 CDD:290200 14/23 (61%)
C2H2 Zn finger 442..490 CDD:275368 10/47 (21%)
C2H2 Zn finger 470..487 CDD:275368 1/16 (6%)
zf-H2C2_2 482..507 CDD:290200 11/24 (46%)
C2H2 Zn finger 498..518 CDD:275368 9/19 (47%)
zf-H2C2_2 510..534 CDD:290200 6/19 (32%)
C2H2 Zn finger 526..546 CDD:275368 2/3 (67%)
zf-H2C2_2 539..563 CDD:290200
C2H2 Zn finger 554..574 CDD:275368
C2H2 Zn finger 582..602 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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