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Protein Alignment EHD2 and Past1

DIOPT Version :10

Sequence 1:	NP_055416.2	Gene:	EHD2 / 30846	HGNCID:	3243	Length:	543	Species:	Homo sapiens
Sequence 2:	NP_731737.1	Gene:	Past1 / 41569	FlyBaseID:	FBgn0016693	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	541	Identity:	343/541 - (63%)
Similarity:	412/541 - (76%)	Gaps:	18/541 - (3%)

- Green bases have known domain annotations that are detailed below.

Human     3 SWLKRGGARGQQPEAIRTVTSALKELYRTKLLPLEEHYRFGAFHSPALEDADFDGKPMVLVAGQY 67
            |:|||   .....|.:..|...||::||:|||||||||:|..||||.|||.|||.|||:|:.|||
  Fly     9 SFLKR---EKNTQEVVENVIGELKKIYRSKLLPLEEHYQFHDFHSPKLEDPDFDAKPMILLVGQY 70

Human    68 STGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGDTEGTVPGNALVVDPDKPFRKLNPFGNTF 132
            |||||:||:||||::.||.|:|||||||.|:|||:.|.||.:|||||||||.|.||.|:.:||.|
  Fly    71 STGKTTFIRYLLERDFPGIRIGPEPTTDRFIAVMYDDKEGVIPGNALVVDPKKQFRPLSKYGNAF 135

Human   133 LNRFMCAQLPNQVLESISIIDTPGILSGAKQRVSRGYDFPAVLRWFAERVDLIILLFDAHKLEIS 197
            ||||.|:.:.:.||.:|||:||||||||.|||:.|||||..||.|||||||.||||||||||:||
  Fly   136 LNRFQCSSVASPVLNAISIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDIS 200

Human   198 DEFSEAIGALRGHEDKIRVVLNKADMVETQQLMRVYGALMWALGKVVGTPEVLRVYIGSFWSQPL 262
            |||..:|.||:||:||||::||||||::.||||||||||||:||||:.||||.||||||||.|||
  Fly   201 DEFRRSIEALKGHDDKIRIILNKADMIDHQQLMRVYGALMWSLGKVLQTPEVARVYIGSFWDQPL 265

Human   263 LVPDNRRLFELEEQDLFRDIQGLPRHAALRKLNDLVKRARLVRVHAYIISYLKKEMPSVFGKENK 327
            ....||||||.||||||||:|.|||:|||||||||:|||||.:|||:||:.|:|:|||||||::|
  Fly   266 RFDANRRLFEDEEQDLFRDLQSLPRNAALRKLNDLIKRARLAKVHAFIIAELRKDMPSVFGKDSK 330

Human   328 KKQLILKLPVIFAKIQLEHHISPGDFPDCQKMQELLMAHDFTKFHSLKPKLLEALDEMLTHDIAK 392
            ||.||..|..::.:||.||.||||||||.:||||:|...||||||||||.||:.:|.||..|||:
  Fly   331 KKDLIKNLGQVYDRIQREHSISPGDFPDIKKMQEVLQHQDFTKFHSLKPHLLDIVDNMLAKDIAR 395

Human   393 LMPLLRQEELESTEVG---VQGGAFEGT---HMGPF-VERGPDEAMEDGEEGSDDEAEWVVTKDK 450
            ||.::.|||:  |.|.   |:||||||.   |:.|| ..:|      :|.:....|.||:..|||
  Fly   396 LMEMIPQEEM--TMVADPIVKGGAFEGVIDDHVSPFGYMKG------EGIDAGYGEHEWICNKDK 452

Human   451 SKYDEIFYNLAPADGKLSGSKAKTWMVGTKLPNSVLGRIWKLSDVDRDGMLDDEEFALASHLIEA 515
            .:.|.||..|.|.|||:||:.||..::.:|||||||.:||||||||.||.||.:|||||.|||..
  Fly   453 PRTDGIFNGLGPVDGKISGATAKQELIKSKLPNSVLSKIWKLSDVDGDGFLDSDEFALALHLINV 517

Human   516 KLEGHGLPANLPRRLVPPSKR 536
            ||||..||..||..|||||||
  Fly   518 KLEGCELPTVLPEHLVPPSKR 538

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.