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Protein Alignment EHD3 and Past1

DIOPT Version :10

Sequence 1:	NP_055415.1	Gene:	EHD3 / 30845	HGNCID:	3244	Length:	535	Species:	Homo sapiens
Sequence 2:	NP_731737.1	Gene:	Past1 / 41569	FlyBaseID:	FBgn0016693	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	528	Identity:	370/528 - (70%)
Similarity:	432/528 - (81%)	Gaps:	8/528 - (1%)

- Green bases have known domain annotations that are detailed below.

Human    10 RRRKDPEVFQTVSEGLKKLYKSKLLPLEEHYRFHEFHSPALEDADFDNKPMVLLVGQYSTGKTTF 74
            |.:...||.:.|...|||:|:||||||||||:||:||||.|||.|||.|||:|||||||||||||
  Fly    13 REKNTQEVVENVIGELKKIYRSKLLPLEEHYQFHDFHSPKLEDPDFDAKPMILLVGQYSTGKTTF 77

Human    75 IRYLLEQDFPGMRIGPEPTTDSFIAVMQGDMEGIIPGNALVVDPKKPFRKLNAFGNAFLNRFVCA 139
            ||||||:||||:|||||||||.|||||..|.||:||||||||||||.||.|:.:||||||||.|:
  Fly    78 IRYLLERDFPGIRIGPEPTTDRFIAVMYDDKEGVIPGNALVVDPKKQFRPLSKYGNAFLNRFQCS 142

Human   140 QLPNPVLESISVIDTPGILSGEKQRISRGYDFAAVLEWFAERVDRIILLFDAHKLDISDEFSEVI 204
            .:.:|||.:||::|||||||||||||.|||||..|||||||||||||||||||||||||||...|
  Fly   143 SVASPVLNAISIVDTPGILSGEKQRIDRGYDFTGVLEWFAERVDRIILLFDAHKLDISDEFRRSI 207

Human   205 KALKNHEDKMRVVLNKADQIETQQLMRVYGALMWSLGKIVNTPEVIRVYIGSFWSHPLLIPDNRK 269
            :|||.|:||:|::|||||.|:.||||||||||||||||::.||||.||||||||..||....||:
  Fly   208 EALKGHDDKIRIILNKADMIDHQQLMRVYGALMWSLGKVLQTPEVARVYIGSFWDQPLRFDANRR 272

Human   270 LFEAEEQDLFRDIQSLPRNAALRKLNDLIKRARLAKVHAYIISSLKKEMPSVFGKDNKKKELVNN 334
            |||.||||||||:||||||||||||||||||||||||||:||:.|:|:||||||||:|||:|:.|
  Fly   273 LFEDEEQDLFRDLQSLPRNAALRKLNDLIKRARLAKVHAFIIAELRKDMPSVFGKDSKKKDLIKN 337

Human   335 LAEIYGRIEREHQISPGDFPNLKRMQDQLQAQDFSKFQPLKSKLLEVVDDMLAHDIAQLMVLVRQ 399
            |.::|.||:|||.|||||||::|:||:.||.|||:||..||..||::||:|||.|||:||.::.|
  Fly   338 LGQVYDRIQREHSISPGDFPDIKKMQEVLQHQDFTKFHSLKPHLLDIVDNMLAKDIARLMEMIPQ 402

Human   400 EESQR---PIQMVKGGAFEGTLH---GPFGHGYGEGAGEGIDDAEWVVARDKPMYDEIFYTLSPV 458
            ||...   ||  ||||||||.:.   .|||:..|||...|..:.||:..:|||..|.||..|.||
  Fly   403 EEMTMVADPI--VKGGAFEGVIDDHVSPFGYMKGEGIDAGYGEHEWICNKDKPRTDGIFNGLGPV 465

Human   459 DGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPA 523
            ||||:||.||:|:::||||||||.|||||:|:|.||.||.||||||.|||.|||||.|||..||.
  Fly   466 DGKISGATAKQELIKSKLPNSVLSKIWKLSDVDGDGFLDSDEFALALHLINVKLEGCELPTVLPE 530

Human   524 HLLPPSKR 531
            ||:|||||
  Fly   531 HLVPPSKR 538

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.