DRSC/TRiP Functional Genomics Resources

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Protein Alignment EHD3 and Eps-15

DIOPT Version :10

Sequence 1:NP_055415.1 Gene:EHD3 / 30845 HGNCID:3244 Length:535 Species:Homo sapiens
Sequence 2:NP_611965.2 Gene:Eps-15 / 37961 FlyBaseID:FBgn0035060 Length:1253 Species:Drosophila melanogaster


Alignment Length:100 Identity:40/100 - (40%)
Similarity:59/100 - (59%) Gaps:1/100 - (1%)


- Green bases have known domain annotations that are detailed below.


Human   430 AGEGIDDAEWVV-ARDKPMYDEIFYTLSPVDGKITGANAKKEMVRSKLPNSVLGKIWKLADIDKD 493
            |..|:.:.:|.: ..|:..|:::|.:|.|.:|.:.|...|..::.||||.|:||.||.|||.|||
  Fly   118 ASGGVANGDWSIGVIDRLKYEQLFESLHPSNGMLPGNKVKGVLMDSKLPMSILGTIWDLADQDKD 182

Human   494 GMLDDDEFALANHLIKVKLEGHELPNELPAHLLPP 528
            |.||..||.:|.||:...|:...:|:.||..|..|
  Fly   183 GNLDMHEFVVAMHLVYQTLQKRTIPSVLPPELRKP 217

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EHD3NP_055415.1 EHD_N <37..56 CDD:465295
EHD 60..300 CDD:206740
G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055 65..72
G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055 91..92
G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055 153..156
G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055 219..222
DUF5600 288..394 CDD:465667
EH 438..531 CDD:197477 37/91 (41%)
Eps-15NP_611965.2 EH 16..82 CDD:238009
EH 126..215 CDD:197477 36/88 (41%)
EH 307..402 CDD:197477
SMC_prok_B <423..>632 CDD:274008
Blue background indicates that the domain is not in the aligned region.

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