Protein Alignment EHD3 and Dap160

DIOPT Version :10

• Sequence 1: NP_055415.1
• Gene: EHD3 / 30845
• HGNCID: 3244
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_001246118.1
• Gene: Dap160 / 35378
• FlyBaseID: FBgn0023388
• Length: 1190
• Species: Drosophila melanogaster
• Alignment Length: 190
• Identity: 62/190 - (32%)
• Similarity: 89/190 - (46%)
• Gaps: 16/190 - (8%)

Human   351 GDFPNLKRMQDQLQAQDFSKFQPLKSKLLEV--VDDMLAHDIAQLMVLVRQEESQRPIQMVKGGA 413
            ||.|:   |..:......|...|||..:..|  |..::|..:|...|:      ..|...|..|.
  Fly   101 GDVPS---MTPRGSTSSLSPLDPLKGIVPAVAPVVPVVAPPVAVATVI------SPPGVSVPSGP 156

Human   414 FEGTLHGPFGH-GYGEGAG--EGIDDAEWVV-ARDKPMYDEIFYTLSPV-DGKITGANAKKEMVR 473
            ...|.:.|..| ...|.|.  |.::..||.| |..|..|.::|...... .|.:||:.|:..:|:
  Fly   157 TPPTSNPPSRHTSISERAPSIESVNQGEWAVQAAQKRKYTQVFNANDRTRSGYLTGSQARGVLVQ 221

Human   474 SKLPNSVLGKIWKLADIDKDGMLDDDEFALANHLIKVKLEGHELPNELPAHLLPPSKRKV 533
            ||||...|.:||.|:|||.||.|:.|||.||..|.:..:.|.::|..||...:||:.||:
  Fly   222 SKLPQVTLAQIWTLSDIDGDGRLNCDEFILAMFLCEKAMAGEKIPVTLPQEWVPPNLRKI 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EHD3	NP_055415.1	EHD_N	<37..56	CDD:465295
		EHD	60..300	CDD:206740
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055	65..72
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055	91..92
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055	153..156
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01055	219..222
		DUF5600	288..394	CDD:465667	12/44 (27%)
		EH	438..531	CDD:197477	38/94 (40%)
Dap160	NP_001246118.1	EH	7..101	CDD:197477	62/190 (33%)
		EH	184..279	CDD:197477	38/94 (40%)
		SMC_prok_B	<368..>615	CDD:274008
		SH3_Intersectin_1	674..728	CDD:212770
		SH3_Intersectin_3	779..830	CDD:212772
		SH3_Intersectin_4	941..998	CDD:212773
		SH3_Intersectin_5	1025..1077	CDD:212774
		RRM_SF	<1125..1175	CDD:473069