Protein Alignment VSX1 and hbn

DIOPT Version :10

• Sequence 1: NP_055403.2
• Gene: VSX1 / 30813
• HGNCID: 12723
• Length: 365
• Species: Homo sapiens
• Sequence 2: NP_788420.1
• Gene: hbn / 47894
• FlyBaseID: FBgn0008636
• Length: 409
• Species: Drosophila melanogaster
• Alignment Length: 296
• Identity: 88/296 - (29%)
• Similarity: 124/296 - (41%)
• Gaps: 93/296 - (31%)

Human   133 KRSDSVSTSDEDSQSEDRNDLKASPTLG--------KRKKRRHRTVFTAHQLEELEKAFSEAHYP 189
            ||.||.:.:|.....::.::|.:|...|        .||.||.||.||..||.:||:||.:..||
  Fly   114 KREDSPTNTDGGLDVDNDDELSSSLNNGHDLSDMERPRKVRRSRTTFTTFQLHQLERAFEKTQYP 178

Human   190 DVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWG---GSSVMAEYGL----YGAMVRHCIP 247
            ||:.||.||::.:|.|.|:||||||||||||||||...   ...::.|.||    .|      ||
  Fly   179 DVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPLG------IP 237

Human   248 LPDSVL----------------------NSAEGGLLGSCAPWLLGMHKK----------SMGMIR 280
            ||...|                      |.|.....|.....|:..|.|          .||:
  Fly   238 LPPHGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAGLLPQHLMAPHYKLPNFHTLLSQYMGL-- 300

Human   281 KPGSEDKLAGLWGSDHFKEGSSQSESGSQRGSDKVSPEN--------GLEDVAIDLSSSARQETK 337
                 ..|.|::|:     |::.:.:.:..|    .|:|        .:..|:...|:|:.:|:.
  Fly   301 -----SNLNGIFGA-----GAAAAAAAASAG----YPQNLSLHAGLSAMSQVSPPCSNSSPRESP 351

Human   338 KV-------H--PGAGAQGGSN-------STALEGP 357
            |:       |  |.||..||..       |||.:.|
  Fly   352 KLVPHPTPPHATPPAGGNGGGGLLTGGLISTAAQSP 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VSX1	NP_055403.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37
		Octapeptide motif	31..38
		PRK14959	<47..>149	CDD:184923	5/15 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..167		11/41 (27%)
		Nuclear localization signal. /evidence=ECO:0000255	161..166		2/4 (50%)
		Homeodomain	165..221	CDD:459649	34/55 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	290..365		21/92 (23%)
hbn	NP_788420.1	Homeodomain	154..210	CDD:459649	34/55 (62%)