Protein Alignment VSX1 and ems

DIOPT Version :10

• Sequence 1: NP_055403.2
• Gene: VSX1 / 30813
• HGNCID: 12723
• Length: 365
• Species: Homo sapiens
• Sequence 2: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Alignment Length: 239
• Identity: 64/239 - (26%)
• Similarity: 84/239 - (35%)
• Gaps: 83/239 - (34%)

Human    44 PAPAGPGQGSGCEGPAVAPCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADV-- 106
            ||...|| |:|       |...||:..:.|.| ..|:|.|       .||.....|.  |.|:
  Fly   245 PAMMHPG-GAG-------PMMMPGMPPAGLVR-PFPMGPG-------GPPMPQGQPG--LPDIKA 291

Human   107 --------PFLPPR-----------------------GPEPAAPLAPSRPPPALGRQKRSDSVST 140
                    |.|||:                       ||..||..|...||.|           .
  Fly   292 LPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHA-----------A 345

Human   141 SDEDSQSEDRNDLKASPTL----GK---------------RKKRRHRTVFTAHQLEELEKAFSEA 186
            ....:....|:..:..|.|    |:               ||.:|.||.|:..||.:||.||...
  Fly   346 QFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESN 410

Human   187 HYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRK--REKRWGG 228
            .|.....|:.||....|.|.:::|||||||.|.::  :|...||
  Fly   411 QYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGG 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VSX1	NP_055403.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37
		Octapeptide motif	31..38
		PRK14959	<47..>149	CDD:184923	29/134 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..167		14/72 (19%)
		Nuclear localization signal. /evidence=ECO:0000255	161..166		2/19 (11%)
		Homeodomain	165..221	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	290..365
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/55 (44%)