Protein Alignment Kcng4 and Shawl

DIOPT Version :9

• Sequence 1: NP_001100905.1
• Gene: Kcng4 / 307900
• RGDID: 1308553
• Length: 506
• Species: Rattus norvegicus
• Sequence 2: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 574
• Identity: 146/574 - (25%)
• Similarity: 222/574 - (38%)
• Gaps: 160/574 - (27%)

  Rat    60 ILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSYEEITQLCDDYDENSQEFFFDRNPSAFGVIVS 124
            |::||.|.||....:||...|.:|||||         |:...:||....|:||||:|..|..|::
  Fly     7 IILNVSGIRYETYKATLKKIPATRLSRL---------TEALANYDPVLNEYFFDRHPGVFTQILN 62

  Rat   125 FLAAGKLVLLREMCALSFREELSYWGIEEANLERCC------------LRKLLKKLEEAAELRRE 177
            :...|||....::|...|.|||.:||::...:|.||            ...:|.||:...|...|
  Fly    63 YYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTE 127

  Rat   178 EAAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMP 242
            |...|....:...|..:.:.|.|...::..|.::|.|....|:.|.:||.|:..:.:|.|:.|.|
  Fly   128 EQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHP 192

  Rat   243 DFRAE--------------------EDKGECARKCYY---------------------------- 259
            .||.:                    :..||..:...|
  Fly   193 GFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGN 257

  Rat   260 -----------------------------------------------------------IFVVET 265
                                                                       .|.||.
  Fly   258 FTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVEL 322

  Rat   266 ICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDESPEAGERPSGSSYLEKV 330
            :|..||.:|..:|.:.:||..||.:.|:|:||..|...:|..:                  ::::
  Fly   323 VCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDV------------------MQRM 369

  Rat   331 GLVLRVLRALRILYVMR---LARHSLGLQTLGLTVRRCAREFGLLLLFLGVAVTLFSPLVYVAEN 392
            |....:|.|..|:.:||   |.|||.||:.|..|.:..|:|..||:.||.:.:..|:.|.|.||.
  Fly   370 GEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEK 434

  Rat   393 -ESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFS 456
             :.....:|.|||...||||::||||||||:.|::.||..|.....|:|:|.:|.|...|...||
  Fly   435 LQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFS 499

  Rat   457 HSYLELKREQEQVQARLR-------RLQNNNSASERELLSDVDDLAPEDLTSPG 503
            ..|...:...:..:.|.|       |.:...:|..|...:.:....|   |.||
  Fly   500 MFYSHTQARSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQTPP---TGPG 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kcng4	NP_001100905.1	BTB	60..167	CDD:197585	39/118 (33%)
		BTB_2	60..159	CDD:280393	36/98 (37%)
		Ion_trans	260..463	CDD:278921	72/206 (35%)
		Ion_trans_2	397..457	CDD:285168	27/59 (46%)
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	37/100 (37%)
		BTB_2	7..97	CDD:280393	36/98 (37%)
		Ion_trans	307..506	CDD:278921	72/216 (33%)
		Ion_trans_2	<449..499	CDD:285168	22/49 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900