DRSC/TRiP Functional Genomics Resources

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Protein Alignment Neto2 and Cubn

DIOPT Version :9

Sequence 1:NP_001100887.2 Gene:Neto2 / 307757 RGDID:1305310 Length:525 Species:Rattus norvegicus
Sequence 2:NP_727348.2 Gene:Cubn / 326235 FlyBaseID:FBgn0052702 Length:3750 Species:Drosophila melanogaster


Alignment Length:545 Identity:124/545 - (22%)
Similarity:188/545 - (34%) Gaps:176/545 - (32%)


- Green bases have known domain annotations that are detailed below.


  Rat    43 TQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFDERYYIEPSFECRFDHLEV 107
            |.||. :..:..|.|.||.||.|||||.||:::|||:....:.||. |...:|.|..|..|:|||
  Fly  1790 TSCGS-IYNALSGKFTSPYYPASYPPNIECLWLLEASMGNSLSLTL-ESMDLEKSESCNRDYLEV 1852

  Rat   108 RDGPFGFSPLIDRYCGMKSPALIRSTGRFMWIKFSSDEELEGLGFRAKYSF------------IP 160
            |:.... ..||..|||.:.|.:|.|.|. :|:||.||::..|.||.|.|::            |.
  Fly  1853 REESES-GQLIGVYCGNEVPGVIHSRGA-IWMKFKSDDDNVGEGFMASYNYEHHNELNGTEGTIE 1915

  Rat   161 DPDFTYLGGILNPIP-------DCQF---------------ELSGADG----------------I 187
            .|.|.  ....:|:|       |.::               .|:..||                |
  Fly  1916 SPHFP--SKFQDPVPYSWRITVDKEYVVAISLLYLRDLDQPHLNFYDGYSDIGARIEVTDPDETI 1978

  Rat   188 VRSSQV--------------------------EQEEKTK------------------PG------ 202
            :.|:.|                          ..||:|:                  ||      
  Fly  1979 ISSTNVVYFTSNRGPFKLNWNRLSKEALRSNRTAEERTRQCGNQLITIDRSVIGFHSPGYPNGYE 2043

  Rat   203 QAVDCIWT-IKATPKAKIYLRFLDYQME-HSNECKRNFVAVYDGSSAIENLKAKFCSTVANDVML 265
            |.::|.|| :.:.|.....|......:| .|.:|..::|.::.||.            :.|...|
  Fly  2044 QDLNCFWTLVPSNPAMHAVLTLSQIDLEIFSEDCIADYVKIFSGSD------------LQNWSEL 2096

  Rat   266 KTGVGVIRMWADEGSRLSRFR-MLFTSFVEPPCTSSTFFCHSNMCINNSLVCNGVQNCAYPWDEN 329
            :|   :..:..:...|:...| .|...||..|..:.|.|             ||:...|      
  Fly  2097 RT---LCSLPTESSDRVFHGRPYLRVEFVTDPSVNKTGF-------------NGIVRTA------ 2139

  Rat   330 HCKEKKKAGLFEQITKTHGTIIGVTSGIVLVLLIISILVQVKQPRKKVMACKTAFNKTGFQEVFD 394
             |                |:.|..:.|:|.:..|:.:|     ||.......|...:.|.:...|
  Fly  2140 -C----------------GSEITASKGLVNITEILKVL-----PRPNHDCVWTIKVRQGRRIKID 2182

  Rat   395 PPHYELFSLREKEISADLADLSEELDNYQKLRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMEL 459
            .|.::|        ..::|..|.:..||..||..:.........  |.....|.....|.||.:.
  Fly  2183 FPDFQL--------QNNMASGSSDCRNYLLLRNGNDEDSPFLGR--GKYCEDVVHEVLNTSSNKA 2237

  Rat   460 PFRNDFAQPQPMKTFNSTFKKSSYT 484
            ..:..||.| |....:..|::..||
  Fly  2238 YIKFHFASP-PRFLVSFRFEELRYT 2261

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Neto2NP_001100887.2 CUB 45..158 CDD:238001 48/112 (43%)
CUB <205..291 CDD:238001 17/88 (19%)
LDLa 297..331 CDD:238060 5/33 (15%)
CubnNP_727348.2 EGF_CA 156..190 CDD:238011
EGF_CA 192..233 CDD:238011
EGF_CA 282..322 CDD:214542
EGF_3 328..366 CDD:289699
EGF 430..457 CDD:278437
EGF_CA 469..503 CDD:238011
CUB 509..622 CDD:238001
CUB 627..737 CDD:238001
CUB 744..849 CDD:294042
CUB 853..970 CDD:238001
CUB 978..1094 CDD:238001
CUB 1100..1211 CDD:238001
CUB 1216..1330 CDD:238001
CUB 1446..1549 CDD:238001
CUB 1554..1667 CDD:238001
CUB 1792..1899 CDD:238001 47/110 (43%)
CUB 1910..1998 CDD:294042 12/89 (13%)
CUB 2019..2133 CDD:238001 25/141 (18%)
CUB 2140..2242 CDD:238001 25/132 (19%)
CUB 2263..2379 CDD:238001
CUB 2385..2511 CDD:238001
CUB 2516..2630 CDD:238001
CUB <2833..2892 CDD:294042
CUB 2898..3008 CDD:238001
CUB 3011..3127 CDD:238001
CUB 3130..3241 CDD:238001
CUB 3254..3363 CDD:238001
CUB 3379..3508 CDD:238001
CUB 3531..3601 CDD:294042
CUB 3623..3733 CDD:238001
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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