DRSC/TRiP Functional Genomics Resources

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Protein Alignment ppardb and Hr96

DIOPT Version :10

Sequence 1:NP_571543.1 Gene:ppardb / 30754 ZFINID:ZDB-GENE-000112-47 Length:517 Species:Danio rerio
Sequence 2:NP_524493.1 Gene:Hr96 / 42993 FlyBaseID:FBgn0015240 Length:723 Species:Drosophila melanogaster


Alignment Length:448 Identity:99/448 - (22%)
Similarity:159/448 - (35%) Gaps:112/448 - (25%)


- Green bases have known domain annotations that are detailed below.


Zfish   152 CRICGDKASGFHYGVHACEGCKGFFRRTIRMKLEYERC--ERACKVQKKSRNKCQYCRFQKCLAL 214
            |.:|||||.|:::....||.||.||||....|.:: .|  .:.|.:...:|..||.||.:|||.:
  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQF-TCPFNQNCDITVVTRRFCQKCRLRKCLDI 70

Zfish   215 GMSHDAIRYGRMPEAEKKKLV---------AGLLAGENPQSSSGADLKTLAKHVNTAYLRNLNM- 269
            ||..:.|.      :|:.||:         |.....||...:..||......|...|...:.|: 
  Fly    71 GMKSENIM------SEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPADSSSSNLD 129

Zfish   270 ------TKKKARSILTGKTSCTA-----------PF----------VIHDMDSLWQAENGLVWNQ 307
                  ..:...|..:|...|:.           |.          ::.|.|...||.|.|:..|
  Fly   130 HYSGSQDSQSCGSADSGANGCSGRQASSPGTQVNPLQMTAEKIVDQIVSDPDRASQAINRLMRTQ 194

Zfish   308 LNGAPLNKEIGVHVFYRCQCTTVETVRELTEFAKNIPGFVDLFLNDQVTLLKYGVHEAIFAMLPS 372
            .....:.:::     ...|...:..|..|.::..:....:..|:|.....|      .:|....|
  Fly   195 KEAISVMEKV-----ISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNAL------TVFTKFMS 248

Zfish   373 LMNKDGL-----LVANGKGFVTREFLRSL-RKPFSEIMEPKFEFAVKFNALELDDSDLALFVAAI 431
             ...||:     :|.:....|  ||:::| ..|     |...:...||    ::....||.:...
  Fly   249 -SPTDGVEIISKIVDSPADVV--EFMQNLMHSP-----EDAIDIMNKF----MNTPAEALRILNR 301

Zfish   432 ILCG----------DRPGLMN----VKQVEQIQ--DGILQA-------LDQH-----LQVHHP-- 466
            ||.|          ||..|::    ||.....:  |.::|:       :..|     ||.|.|  
  Fly   302 ILSGGGANAAQQTADRKPLLDKEPAVKPAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGV 366

Zfish   467 ------DSSHLFPKLLQKM-ADLRQLVTENAQLVQMIKKTESETSLHPLLQEIYKDMY 517
                  .|||..|.:.... .||:..:..|......:....|..|:..:|.|:.:..|
  Fly   367 GEQPSTSSSHPLPYIANSPDFDLKTFMQTNYNDEPSLDSDFSINSIESVLSEVIRIEY 424

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ppardbNP_571543.1 NR_DBD_Ppar 151..234 CDD:143523 30/83 (36%)
NR_LBD_PPAR 250..516 CDD:132730 63/336 (19%)
Hr96NP_524493.1 NR_DBD_CAR 5..98 CDD:143524 33/97 (34%)
NR_LBD 462..>573 CDD:472173
NR_LBD_F1 523..702 CDD:132727
Blue background indicates that the domain is not in the aligned region.

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