DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pparda and Hr96

DIOPT Version :9

Sequence 1:	XP_699900.6	Gene:	pparda / 30750	ZFINID:	ZDB-GENE-990415-212	Length:	496	Species:	Danio rerio
Sequence 2:	NP_524493.1	Gene:	Hr96 / 42993	FlyBaseID:	FBgn0015240	Length:	723	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	103/468 - (22%)
Similarity:	160/468 - (34%)	Gaps:	150/468 - (32%)

- Green bases have known domain annotations that are detailed below.

Zfish   129 CRICGDRASGFHYGVHACEGCKGFFRRTIRMKLEYERC--ERSCKIQKKSRNKCQFCRFQKCLML 191
            |.:|||:|.|:::....||.||.||||....|.:: .|  .::|.|...:|..||.||.:|||.:
  Fly     7 CAVCGDKALGYNFNAVTCESCKAFFRRNALAKKQF-TCPFNQNCDITVVTRRFCQKCRLRKCLDI 70

Zfish   192 GMSHDAIRYGRMPEAE---KRKLVAGLLAGERGSQN---------SNESDLKTLAKRVNNAYLKN 244
            ||..:.|    |.|.:   ||:.:....|..|..:|         ..|.|.|..|    ::...|
  Fly    71 GMKSENI----MSEEDKLIKRRKIETNRAKRRLMENGTDACDADGGEERDHKAPA----DSSSSN 127

Zfish   245 LNM-----------TKKKARNILTGKTSASTP----------------FVIHDMDSLVQAENGLV 282
            |:.           :.....|..:|: .||:|                .::.|.|...||.|.|:
  Fly   128 LDHYSGSQDSQSCGSADSGANGCSGR-QASSPGTQVNPLQMTAEKIVDQIVSDPDRASQAINRLM 191

Zfish   283 WNQVIHGAPPNKEIGVHVFYR---CQCTTVETVRELTEFSKSIPGFIDLFLN------------- 331
            ..|        || .:.|..:   .|...:..|..|.::.......|..|:|
  Fly   192 RTQ--------KE-AISVMEKVISSQKDALRLVSHLIDYPGDALKIISKFMNSPFNALTVFTKFM 247

Zfish   332 ----DQVTLLKYGVHEA--IFAMLPSLMN--KDGLLVANGRGFVTREFLRSL------------- 375
                |.|.::...|...  :...:.:||:  :|.:.:.|.......|.||.|
  Fly   248 SSPTDGVEIISKIVDSPADVVEFMQNLMHSPEDAIDIMNKFMNTPAEALRILNRILSGGGANAAQ 312

Zfish   376 ----RKPFSEIMEPKFEFAVKFNALELDDSDLAL------------FVAAIIL------CGDRPG 418
                |||..: .||    ||| .|...:.:|..:            ..||:.|      .|::|.
  Fly   313 QTADRKPLLD-KEP----AVK-PAAPAERADTVIQSMLGNSPPISPHDAAVDLQYHSPGVGEQPS 371

Zfish   419 LMNVHQVEKIQDSILQALNQHLQLNHPDGRFIFPRLLQKLADLRQLVTENAQLVQKIKKTESETS 483
            ..:.|.:..|             .|.||            .||:..:..|......:....|..|
  Fly   372 TSSSHPLPYI-------------ANSPD------------FDLKTFMQTNYNDEPSLDSDFSINS 411

Zfish   484 LHPLLQEIYRDMY 496
            :..:|.|:.|..|
  Fly   412 IESVLSEVIRIEY 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pparda	XP_699900.6	NR_DBD_Ppar	128..211	CDD:143523	33/86 (38%)
pparda	XP_699900.6	NR_LBD_PPAR	228..495	CDD:132730	65/352 (18%)
Hr96	NP_524493.1	NR_DBD_CAR	5..98	CDD:143524	34/95 (36%)
		NR_LBD	462..>573	CDD:299703
		NR_LBD_F1	523..702	CDD:132727
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593352
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	2	1.890