Protein Alignment Kcng2 and Shawl

DIOPT Version :9

• Sequence 1: NP_001100842.1
• Gene: Kcng2 / 307234
• RGDID: 1309521
• Length: 480
• Species: Rattus norvegicus
• Sequence 2: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 587
• Identity: 155/587 - (26%)
• Similarity: 228/587 - (38%)
• Gaps: 168/587 - (28%)

  Rat    33 VIINVGGCRVRLAWAALARCPLARLERLRACRGHDELLRVCDDYDVSRDEFFFDRSPCAFRAIVA 97
            :|:||.|.|.....|.|.:.|..||.||      .|.|.   :||...:|:||||.|..|..|:.
  Fly     7 IILNVSGIRYETYKATLKKIPATRLSRL------TEALA---NYDPVLNEYFFDRHPGVFTQILN 62

  Rat    98 LLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCC----------------LRRLRRREEEAAE 146
            ..|.|||......|...|.:||.:||:|..::|.||                |.:|....|:..|
  Fly    63 YYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTE 127

  Rat   147 ARATPPAR--GPQTSPGRALGSGRL---ERGRRRLRDVVENPHSGLAGKLFAYVSVAFVAVTAVG 206
            .:.   ||  |.:    .||.:|.|   :|.:.::..:.:.|.|....|:.|.:||.|:.|:.:.
  Fly   128 EQI---ARLFGFE----EALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVIS 185

  Rat   207 LCLSTMPDVR------------------------------------------------------- 216
            .||.|.|..|
  Fly   186 FCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNY 250

  Rat   217 -----------------AEEERGECSTKCRNL--------------------------------- 231
                             |..:.|:.....||:
  Fly   251 TSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHE 315

  Rat   232 --FVLETVCVAWFSFEFLLRSLQAESKCAFLRTPLAIIDILAILPFYVSLLAGLAAGPTGSKMLE 294
              |.:|.||..||..|.::|.:.:.:...|:::|:.|||..|.|.||..::         .:|.|
  Fly   316 AFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDVM---------QRMGE 371

  Rat   295 RAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTVRRCAREFGLLLLFLCVAMALFAPLVHLAER- 358
            ..|| |.....:|::.:.:|.|||.|||.|..|.:..|:|..||:.||.:.:..||.|.:.||:
  Fly   372 YTGL-LEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKL 435

  Rat   359 ELGAHRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSR 423
            :......|.|:|...|||:::||||||||:.|::.||..|.....|:|:|.:|.||..|...||.
  Fly   436 QDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSM 500

  Rat   424 SYSELKEQQQRAASPE------PVLREDSTRDDSTRSASATEDSSQDPETAG---AAGSLP-GPV 478
            .||   ..|.|:..|:      ||.:....|:.:......|....|.|.|..   |.|.:| |..
  Fly   501 FYS---HTQARSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQTPPTGPGLVAGGVVPVGAG 562

  Rat   479 GP 480
            ||
  Fly   563 GP 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kcng2	NP_001100842.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		BTB_POZ_Kv6_KCNG	33..127	CDD:349691	35/93 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..167		6/24 (25%)
		Ion_trans	190..429	CDD:395416	87/346 (25%)
		Selectivity filter. /evidence=ECO:0000250	382..387		4/4 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	429..480		14/60 (23%)
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	37/100 (37%)
		BTB_2	7..97	CDD:280393	36/98 (37%)
		Ion_trans	307..506	CDD:278921	72/211 (34%)
		Ion_trans_2	<449..499	CDD:285168	22/49 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010