DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdx1 and Antp

DIOPT Version :9

Sequence 1:	NP_571518.2	Gene:	pdx1 / 30721	ZFINID:	ZDB-GENE-990415-122	Length:	246	Species:	Danio rerio
Sequence 2:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	69/221 - (31%)
Similarity:	91/221 - (41%)	Gaps:	75/221 - (33%)

- Green bases have known domain annotations that are detailed below.

Zfish    33 PPCLYMRQAHSVYA------------SPLGAQD--QPNLTDI--TSYNMSSRDDLAG-------- 73
            ||.:.....|.:.|            :.||..|  .|::|::  ..:||......:|
  Fly   180 PPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVTEVHQNHHNMGMYQQQSGVPPVGAPP 244

Zfish    74 -----------------PHLHLPQTSQTSLQSLGGYGDSLDLCGDRNRYHLP---FPWMKSTKSH 118
                             |..|.|.:...:.||.|                :|   :|||:|
  Fly   245 QGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSG----------------MPSPLYPWMRS---- 289

Zfish   119 THAWKGQWTGPYMVEAEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELALTLSLTERHIKI 183
                       ...:.:|.||.|..|||.|.|||||||.||:|::|.||:|:|..|.||||.|||
  Fly   290 -----------QFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKI 343

Zfish   184 WFQNRRMKWKKEEDKRRARGVDPEQD 209
            ||||||||||||...:...|...|.|
  Fly   344 WFQNRRMKWKKENKTKGEPGSGGEGD 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdx1	NP_571518.2	Homeobox	140..193	CDD:278475	36/52 (69%)
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	28/156 (18%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	37/52 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810