DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dnmt3bb.2 and CG15306

DIOPT Version :9

Sequence 1:	NP_571461.1	Gene:	dnmt3bb.2 / 30659	ZFINID:	ZDB-GENE-990712-11	Length:	1448	Species:	Danio rerio
Sequence 2:	NP_001259403.1	Gene:	CG15306 / 31961	FlyBaseID:	FBgn0030191	Length:	357	Species:	Drosophila melanogaster

Alignment Length:	217	Identity:	54/217 - (24%)
Similarity:	100/217 - (46%)	Gaps:	35/217 - (16%)

- Green bases have known domain annotations that are detailed below.

Zfish    16 ELLDWLNGLLQATFSQVEDTCSGAAFCQLMDIIQPGSIDVTKVNFTAEENLDILNNYNLLQEAFS 80
            ::|||.|..||.....:|..|:|||:|.||.::.|..|::.:|.|.:.:..:.:||:..||:||:
  Fly    23 DILDWFNETLQCNLINIEQLCTGAAYCNLMHMLYPKLINLKRVKFFSNQEYEYVNNFKELQKAFN 87

Zfish    81 KAQIQKELELTLLVNGDIMTTCDLLTWFKDMYDHNFAKQKCNPQVAFI--KPEVVSLKSSR---- 139
            |..:....|:..|:.|..:.......||:..::.|..|.||....|.:  ..:.:.:.||:
  Fly    88 KVNVSLPAEVNDLIKGHRVENFKFAVWFRHFFNVNHTKDKCAGYDALVARDHQNIGIGSSKLTTK 152

Zfish   140 -EFETIE-------------KENVSSLYNTEETSSNQKTQHVEKTSQESVSWSPLTSFIRKYGSS 190
             .|..::             :..::|...|.:.:.::.:||.:|..::|          |..||.
  Fly   153 DRFRLVKVKTTAIRGKVATCQATINSSLCTGKANQDEDSQHTDKKDEDS----------RDQGSQ 207

Zfish   191 TLTDDESNNVNS--KDCPGQKS 210
            .   ::|..::|  |||..|.|
  Fly   208 Y---EDSPGMDSQYKDCRDQDS 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dnmt3bb.2	NP_571461.1	CH	16..>81	CDD:278723	24/64 (38%)
		Dnmt3b_related	790..873	CDD:99896
		PHD_SF	1020..1139	CDD:304600
		Dcm	1163..>1325	CDD:223348
CG15306	NP_001259403.1	CH	20..103	CDD:278723	27/79 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5217
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810