|
Human 303 PVEDEHSTLLILGVLLTLRYLVPLLQQQVKDTSLKGSFGVTRKEMEVSPS-------AEQLVQVY 360
|..::....::|..||..::..|:...:.:|..|| .|. |.:.:|:.|| ...|...|
Yeast 3 PEVEQELAHILLTELLAYQFASPVRWIETQDVFLK-DFN-TERVVEIGPSPTLAGMAQRTLKNKY 65
Human 361 E-----LTLHHTQHQDHNVVTGALELL------QQLFRTPPPELLQTLTAVGGIGQLTAAKEESG 414
| |:||. |:| ::::.||.|..| |||||.
Yeast 66 ESYDAALSLHR-------------EILCYSKDAKEIYYTPDPSEL-------------AAKEEP- 103
Human 415 GRSRSGSIVELIAGGGSSCSPVLSRKQKGKVLLGEEEALEDDSESRSDVSSSALTASVKDEISGE 479
.:|||......:.:...::|..|.|
Yeast 104 ---------------------------------AKEEAPAPTPAASAPAPAAAAPAPV------- 128
Human 480 LAASSGVSTPGSAGHDIITEQPRSQ---HTLQADSVDLASCDLTSSATDGD--------EEDILS 533
..:.|.:|..:|..|..::. |.|.|..:..:...:..|.|..| :.:||.
Yeast 129 -----AAAAPAAAAAEIADEPVKASLLLHVLVAHKLKKSLDSIPMSKTIKDLVGGKSTVQNEILG 188
Human 534 HSSSQVSAVPSDPAMDLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEI------VLDG----- 587
....:....|..| ..:|:.:.::|..:....|:....||.: .:.|
Yeast 189 DLGKEFGTTPEKP---------EETPLEELAETFQDTFSGALGKQSSSLLSRLISSKMPGGFTIT 244
Human 588 TDNQYLGLQIGQPQDEDEEATGILPDEASE--AFRNSSMALQQAHLLKNMSHCRQPSDSSVDKFV 650
...:||..:.|.|....: |:|....|. |.|..|.|..:|.| ||...|:
Yeast 245 VARKYLQTRWGLPSGRQD---GVLLVALSNEPAARLGSEADAKAFL-----------DSMAQKY- 294
Human 651 LRDEATEPGDQENKPCRIKGDIGQSTDDDSAPLVHCVRLLSASFLLTGGKNVLVPDRDV--RVSV 713
|:..|...:......|..|... ...|:.:..|....:..|..| |..:
Yeast 295 ----ASIVGVDLSSAASASGAAGAGA------------AAGAAMIDAGALEEITKDHKVLARQQL 343
Human 714 KALALSCVGAAVALHPESFFSKLYKVPLDTTE---YPEEQYVSDILNYIDH-----GDPQVRGAT 770
:.|| :..|:.||..| ..|:..|:::...:|: |:..|.|
Yeast 344 QVLA-----------------RYLKMDLDNGERKFLKEKDTVAELQAQLDYLNAELGEFFVNG-- 389
Human 771 AILCGTLICSILSRSRFHVGD--WMGTIRTLTGNTFSLADCIPLLRKTLKDESSVTCKLACTAVR 833
:.:..||.:....| |....::|....|. ::...||:
Yeast 390 -------VATSFSRKKARTFDSSWNWAKQSLLSLYFE------IIHGVLKN-------------- 427
Human 834 NCVMSLCSSSYSELGLQLIIDVLTLRNSSYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGAHH 898
:..:::.:.:.:.|.| ...|::.: ::.:.:..|.|.||
Yeast 428 -------------VDREVVSEAINIMNRS----NDALIKFM---EYHISNTDETKGEN------- 465
Human 899 YTGLLKLQERVLNNVVIHLLGDEDPRVRHVAAASLIRLVPKLFYKCDQGQADPVVAVARDQSSVY 963
|..:..|.|:::.|....| |.||..:.||..: .|..|:.::.:..|
Yeast 466 YQLVKTLGEQLIENCKQVL--DVDPVYKDVAKPT-----------------GPKTAIDKNGNITY 511
Human 964 LKLLMHETQPPSHFSVSTITRIYRGYNLLPSIT---DVTMENNLSRVIAAVSHEL----ITSTTR 1021
::.|.. .|..:::..:...|...|| ..|:|.:|:||..|:|.:. |:|:||
Yeast 512 -------SEEPRE-KVRKLSQYVQEMALGGPITKESQPTIEEDLTRVYKAISAQADKQDISSSTR 568
Human 1022 ALTFGCCEALCLLSTAFPVCIWSLGWHCGVPPLSASDESRKSCTVGMATMILTLLSSAWFPLDLS 1086
. |...|.|..... |.:|.|...|.|..:|.|.:
Yeast 569 V------EFEKLYSDLMKF-------------LESSKEIDPSQTTQLAGMDV------------- 601
Human 1087 AHQDALILAGNLLAASAP-KSLRSSWASEEEANPAATKQEEVWPALGDRALVPMVEQLFSHLLKV 1150
:|||........||.| ||..|...| :|...|..|.|..|...|..:..:...|..
Yeast 602 --EDALDKDSTKEVASLPNKSTISKTVS-------STIPRETIPFLHLRKKTPAGDWKYDRQLSS 657
Human 1151 INICAHVLDDVAPGPAIKAALPSLTNPPSLSPIRRKGKEKEPGEQASVPLSPKKGSEASAASRQS 1215
: .||.:. |||...:|.......|...|| .|: |:|......|.
Yeast 658 L-----FLDGLE-----KAAFNGVTFKDKYVLITGAGK-------GSI------GAEVLQGLLQG 699
Human 1216 DTSGPVTTSKSSSLGSFYHLPSYLK---------LHDVLKATHANYKVTLDLQNSTEKFGGFLRS 1271
.....||||:.|...:.|:...|.| :....:.:..:.:..::....|||.||.
Yeast 700 GAKVVVTTSRFSKQVTDYYQSIYAKYGAKGSTLIVVPFNQGSKQDVEALIEFIYDTEKNGGL--- 761
Human 1272 ALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATV-----CVQQ--------------- 1316
..| |..|:..|.:.:.|..:|.|.. ||.|:...|:..: ||::
Yeast 762 GWD-LDAIIPFAAIPEQGIELEHIDS--KSEFAHRIMLTNILRMMGCVKKQKSARGIETRPAQVI 823
Human 1317 ---------------------LLKTLF-----------------------GTNLASQFDGLSSNP 1337
.|:||| ||.| :|:|.
Yeast 824 LPMSPNHGTFGGDGMYSESKLSLETLFNRWHSESWANQLTVCGAIIGWTRGTGL------MSANN 882
Human 1338 SKSQGRAQRLGSSS-------------VRPGLYHYCFMAPY-------THFTQALAD--ASLRNM 1380
..::| .:::|..: :.|.:...|..:|. ..|...|.: |.||
Yeast 883 IIAEG-IEKMGVRTFSQKEMAFNLLGLLTPEVVELCQKSPVMADLNGGLQFVPELKEFTAKLR-- 944
Human 1381 VQAEQENDTSGWFDVLQKVSTQLKTNLTSVTKNRADKNAIHNHIRLFEP-----LVIKALKQYTT 1440
::..:|| :|.:.||.:.......|..|.|| |.:..:.: :| |....||.|
Yeast 945 ---KELVETS---EVRKAVSIETALEHKVVNGNSAD--AAYAQVEI-QPRANIQLDFPELKPY-- 998
Human 1441 TTCVQLQKQVLDLL-AQLVQLRVNYCLLDSDQVFI--GFVLKQFEYIEVGQFR------ESEAI- 1495
|||..:. |:|.. |||.::|.: ||. |||.:. |.||.
Yeast 999 -------KQVKQIAPAELEG------LLDLERVIVVTGFA-------EVGPWGSARTRWEMEAFG 1043
Human 1496 ---IPNIFFFLVLLSYERYHSKQIIGIP-------KIIQLCD--GIMASGRKAVTH--AIPALQP 1546
:........::.:..||:..:.|.| |..:..| .:.|....::.. .|..::|
Yeast 1044 EFSLEGCVEMAWIMGFISYHNGNLKGRPYTGWVDSKTKEPVDDKDVKAKYETSILEHSGIRLIEP 1108
Human 1547 IVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQCHKENEDKWKRLSRQ 1611
:|| .|.|. ::.|..:||:| .:.||.| :..||..:::|.....
Yeast 1109 ---ELF--NGYNP----EKKEMIQEVIV---------EEDLEPF-----EASKETAEQFKHQHGD 1150
Human 1612 IADII-LPMLAKQQMHIDSHEALGVLNTL-FEILAPSSLRPVDMLLRSMFVTPNTMASVSTVQLW 1674
..||. :|...:..:.:.....|.:...| |:.|....: |.....::..::.:.::.|..:.|:
Yeast 1151 KVDIFEIPETGEYSVKLLKGATLYIPKALRFDRLVAGQI-PTGWNAKTYGISDDIISQVDPITLF 1214
Human 1675 ISGILAILRVLISQSTED 1692
: :::::...|:....|
Yeast 1215 V--LVSVVEAFIASGITD 1230
| 
