DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fli1 and Ets97D

DIOPT Version :9

Sequence 1:	XP_021323256.1	Gene:	fli1 / 30619	ZFINID:	ZDB-GENE-980526-426	Length:	474	Species:	Danio rerio
Sequence 2:	NP_001263000.1	Gene:	Ets97D / 43236	FlyBaseID:	FBgn0004510	Length:	484	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	122/383 - (31%)
Similarity:	177/383 - (46%)	Gaps:	110/383 - (28%)

- Green bases have known domain annotations that are detailed below.

Zfish    36 LFEPPYAAAAPL----------PKTDMTASGTQDYGQTHKINPIPPQQEWINQPVRVNVKREYDH 90
            :.:|..||.|.|          |:|....|.:.:                  .|::..:||.  |
  Fly   119 VLKPTEAALAALAEEVVGQLSPPETASQKSSSSE------------------SPIKTPLKRM--H 163

Zfish    91 INGSRESPVDCSVGKCNKMVGGTEASQMNYTGYMDEKCAPPPNMTTNERRVIVP--AGEYCINPS 153
            ...|.|..|:   ||..|.|       :|:.  :|.|      ....:.|:.:|  |.|
  Fly   164 KEDSEEESVE---GKDVKPV-------LNWV--LDSK------FKREQIRLKIPEAANE------ 204

Zfish   154 LWSPDHVRQWLDWAIKEYGLQEIDTAMFHSTDGKELCKMSKDDFLRLTSVYNTEVLLSHLNYLRE 218
             |:..||..||:||:|::.|..|:.:.: ..:|:|||.|:.::|.:........:..:||..|:|
  Fly   205 -WTHAHVTYWLEWAVKQFELVGINMSDW-QMNGQELCAMTHEEFNQKLPRDPGNIFWTHLQLLKE 267

Zfish   219 -----------------------SSSSISYNTPSHADQSPRLAAKDDASYDAVRRTGWSNNMHSG 260
                                   |::|||.|:........|:..|   ||.:|
  Fly   268 CNFVSVVHKRAEEQRKPKQPRIMSANSISTNSGGSLSLEQRIMRK---SYQSV------------ 317

Zfish   261 KGSPTVVSQSVSKNPDQPRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANAGCITWE 325
            |.|.:|.|.:.|.||..       |..:|       :..:||:||||||||:|:|..:...|.|.
  Fly   318 KSSDSVESTTSSMNPSN-------YTTIG-------SGNNGQVQLWQFLLEILTDCEHTDVIEWV 368

Zfish   326 GTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKFD 383
            ||.||||:||||.|||.|||:|:||.|||:|||||||||||.::::||.|||:|||||
  Fly   369 GTEGEFKLTDPDRVARLWGEKKNKPAMNYEKLSRALRYYYDGDMISKVSGKRFAYKFD 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fli1	XP_021323256.1	SAM_PNT-FLI-1	131..226	CDD:188883	28/119 (24%)
fli1	XP_021323256.1	ETS	302..385	CDD:197710	56/82 (68%)
Ets97D	NP_001263000.1	GABP-alpha	48..123	CDD:288472	0/3 (0%)
		SAM_PNT-GABP-alpha	184..272	CDD:176084	26/103 (25%)
		ETS	345..429	CDD:197710	56/82 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3806
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810