Protein Alignment hsp90ab1 and Hsp83

DIOPT Version :10

• Sequence 1: NP_571385.2
• Gene: hsp90ab1 / 30573
• ZFINID: ZDB-GENE-990415-95
• Length: 725
• Species: Danio rerio
• Sequence 2: NP_523899.1
• Gene: Hsp83 / 38389
• FlyBaseID: FBgn0001233
• Length: 717
• Species: Drosophila melanogaster
• Alignment Length: 718
• Identity: 571/718 - (79%)
• Similarity: 642/718 - (89%)
• Gaps: 4/718 - (0%)

Zfish     9 EEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKID 73
            ||||||||||||||||||||||||||||||||||:||||||||||||||||||:||||||:|.|.
  Fly     3 EEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIK 67

Zfish    74 IIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLV 138
            :|||....|||:|||||||||:||:||||||||||||||||||||||||||||||||||||||||
  Fly    68 LIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLV 132

Zfish   139 AEKVTVITKHNDDEQYAWESSAGGSFTVKVDHGEPIGRGTKVILHLKEDQTEYIEEKRVKEVVKK 203
            |:||||.:|:||||||.|||||||||||:.|:.||:|||||::|::|||||:|:||.::||:|.|
  Fly   133 ADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNK 197

Zfish   204 HSQFIGYPITLYVEKERDKEISDDEAEEEKAEKEEKEEEGEDKPKIEDVGSDDEEDTKDKDKKKK 268
            |||||||||.|.|||||:||:|||||::||.|.:||:|...|:|||||||.|::.|.||||.|||
  Fly   198 HSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKK 262

Zfish   269 KKIKEKYIDQEELNKTKPIWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF 333
            |.|||||.:.||||||||||||||||||.||||||||||||||||||||||||||||||||||||
  Fly   263 KTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF 327

Zfish   334 IPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSK 398
            ||||.|||||||:||:|||||||||||||||||:||||||||::|||||||||||||||||||:|
  Fly   328 IPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNK 392

Zfish   399 ILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGD 463
            :|||||||:|||.:||..||.|||:|||||||.||||||||:||||.||.||::.||:.:|.|||
  Fly   393 VLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGD 457

Zfish   464 EMTSLTEYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFD 528
            :..||.:||||||:|||.:|:|||||||||::|||||||..|||||:|||||||||.:|.||::.
  Fly   458 DFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYK 522

Zfish   529 GKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTS 593
            ||.|||||||||||||||.||||.||||||||:||||||.|||.|||||.||||||.||||||||
  Fly   523 GKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTS 587

Zfish   594 TYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVILLF 658
            .:||:||||||||||||||.:|||||..||.|||||||||:|||||||:||||||||||||||||
  Fly   588 QFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADADKNDKAVKDLVILLF 652

Zfish   659 ETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDEDVPVEEPSSAAAPEDIPPL-EGDDDASRME 722
            ||:|||||||||.||.|::||||||||||||||||.:..::..||.   |.|.| |..:|||.||
  Fly   653 ETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAG---DAPSLVEDTEDASHME 714

Zfish   723 EVD 725
            |||
  Fly   715 EVD 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hsp90ab1	NP_571385.2	HSP90	13..725	CDD:481033	565/712 (79%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..269		30/48 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	691..725		15/34 (44%)
		TPR repeat-binding	721..725		3/3 (100%)
Hsp83	NP_523899.1	HSP90	6..717	CDD:481033	566/713 (79%)