Protein Alignment pax6a and ey

DIOPT Version :9

• Sequence 1: XP_009296153.1
• Gene: pax6a / 30567
• ZFINID: ZDB-GENE-990415-200
• Length: 459
• Species: Danio rerio
• Sequence 2: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Alignment Length: 595
• Identity: 254/595 - (42%)
• Similarity: 295/595 - (49%)
• Gaps: 203/595 - (34%)

Zfish    29 NEGHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNENVSNGC 93
            :|.||||||||||||.||||||||||||||||||||||||||||||              |||||
  Fly    95 DECHSGVNQLGGVFVGGRPLPDSTRQKIVELAHSGARPCDISRILQ--------------VSNGC 145

Zfish    94 VSKILGRYYETGSIRPRAIGGSKPRVATPEVVGKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNI 158
            ||||||||||||||||||||||||||||.|||.||:|||||||||||||||||||.|.|||||||
  Fly   146 VSKILGRYYETGSIRPRAIGGSKPRVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNI 210

Zfish   159 PSVSSINRVLRNLASEKQQM--------------------------------------------- 178
            ||||||||||||||::|:|.
  Fly   211 PSVSSINRVLRNLAAQKEQQSTGSGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLM 275

Zfish   179 ------------GA---------DGMYEKLRMLN-------------------GQT----GTWGT 199
                        ||         :.:|||||:||                   ||:    ||..:
  Fly   276 QTATPLNSSESGGASNSGEGSEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSS 340

Zfish   200 RP-------------------------GWYPG-------TSVP------------------GQPN 214
            .|                         .|||.       :|.|                  ..||
  Fly   341 HPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPN 405

Zfish   215 ----------QDGC---------------QQSD----GGGENTNSISSNGEDSDETQMRLQLKRK 250
                      |..|               .|||    |.|||:|..:||..::::.|.||.||||
  Fly   406 DIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARLILKRK 470

Zfish   251 LQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQ 315
            |||||||||.:||::||||||||||||||||||||.||.||||||||||||||||||||||||||
  Fly   471 LQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQ 535

Zfish   316 RRQASNSSSHIPISSSFSTSVYQPIPQPTTPV-SFTSGSMLGRSDTALTNTYSALPPMPSFTMAN 379
            ||..:::.:....||:.:|:.....|...:.. |..|||..|.|.:.:....|     ||....|
  Fly   536 RRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSS-----PSTLSTN 595

Zfish   380 -NLPMQPSQTSSYSCMLP--------TSPSVNGRSYD------TYTPPHMQAHMNSQSMAASGTT 429
             |.|...:...|.....|        ||.:.|||..:      :..|..:..|.|:..:.::|..
  Fly   596 VNAPTLGAGIDSSESPTPIPHIRPSCTSDNDNGRQSEDCRRVCSPCPLGVGGHQNTHHIQSNGHA 660

Zfish   430 STGLISPGVS 439
            ....:.|.:|
  Fly   661 QGHALVPAIS 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pax6a	XP_009296153.1	PAX	31..169	CDD:128645	116/137 (85%)
		Homeobox	255..307	CDD:306543	45/51 (88%)
		Retinal	341..>459	CDD:330657	26/115 (23%)
ey	NP_001014693.1	PAX	98..221	CDD:128645	116/136 (85%)
		Homeobox	475..527	CDD:278475	45/51 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	240	1.000	Domainoid score	I2213
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152885at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR45636
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	7	7.550