DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pax6a and al

DIOPT Version :9

Sequence 1:	XP_009296153.1	Gene:	pax6a / 30567	ZFINID:	ZDB-GENE-990415-200	Length:	459	Species:	Danio rerio
Sequence 2:	NP_722629.1	Gene:	al / 33208	FlyBaseID:	FBgn0000061	Length:	408	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	90/268 - (33%)
Similarity:	120/268 - (44%)	Gaps:	62/268 - (23%)

- Green bases have known domain annotations that are detailed below.

Zfish   205 PGTSVP--------------GQPNQDGCQQSDGGGENTNSISSNGEDSDETQMRLQLKRKLQRNR 255
            ||:|..              |.|:  |...:.||   |||..|:| :||........|||.:|.|
  Fly    31 PGSSAASAGAALTVSMSVSGGAPS--GASGASGG---TNSPVSDG-NSDCEADEYAPKRKQRRYR 89

Zfish   256 TSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQAS 320
            |:||..|:|.|||.|.||||||||.||.||.||.|.||||||||.|||||||::||:..|
  Fly    90 TTFTSFQLEELEKAFSRTHYPDVFTREELAMKIGLTEARIQVWFQNRRAKWRKQEKVGPQ----- 149

Zfish   321 NSSSHIPISSSFSTSVYQP-IPQPTTPVSFTSGSMLGRSDTALTNTYSALPPMPSFTMANNL--P 382
               ||          .|.| :|              |.:.|..|...:||||.|...:...|  |
  Fly   150 ---SH----------PYNPYLP--------------GGAATMQTVVGAALPPNPFTHLGFQLRKP 187

Zfish   383 MQPSQTSSYSCM----LPTSPSVNGRSYDTY--TPPHMQAHMNSQSMAASGTTSTGLISPGVSVP 441
            ......::.:..    |..:|.:....::.:  .||||..| ....|.:..::...|::...:||
  Fly   188 FDAQHAANLAAFRYPHLSAAPMIPSGYFNQFQRAPPHMLPH-GMAGMYSPSSSFQSLLANMTAVP 251

Zfish   442 VQVPGSEP 449
            ...|..:|
  Fly   252 RGTPLGKP 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pax6a	XP_009296153.1	PAX	31..169	CDD:128645
		Homeobox	255..307	CDD:306543	38/51 (75%)
		Retinal	341..>459	CDD:330657	24/117 (21%)
al	NP_722629.1	Homeobox	89..141	CDD:278475	38/51 (75%)
al	NP_722629.1	OAR	374..391	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910