DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment foxd3 and FoxK

DIOPT Version :9

Sequence 1:	NP_571365.2	Gene:	foxd3 / 30548	ZFINID:	ZDB-GENE-980526-143	Length:	371	Species:	Danio rerio
Sequence 2:	NP_001261701.1	Gene:	FoxK / 39252	FlyBaseID:	FBgn0036134	Length:	760	Species:	Drosophila melanogaster

Alignment Length:	206	Identity:	70/206 - (33%)
Similarity:	92/206 - (44%)	Gaps:	62/206 - (30%)

- Green bases have known domain annotations that are detailed below.

Zfish    96 KPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYR-EKFPAWQNSIRHNLSLNDCFVKIPR 159
            ||||||..||..||..:|.|:||||||..||...:|||| |....||||||||||||..|:|:.|
  Fly   453 KPPYSYAQLIVQAISAAPDKQLTLSGIYSFIVKHYPYYRKETNKGWQNSIRHNLSLNRYFIKVAR 517

Zfish   160 EPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQPDILRDQTALMMQSFGAYGIGNPYGRHY 224
            ....||||::|.:||.|.....:.|:.:||:|                    .:.|...|||
  Fly   518 SQDEPGKGSFWRIDPDSGAKLIDHSYKKRRQR--------------------SSQGFRPPYG--- 559

Zfish   225 GIHPAAYTHPAALQYPYIPPVGPMLPPAVPLLPSAELNRKAFSSQLSPSLQLQLNSLSTASIIKS 289
                                    :|.:.|:.||...|    |.:.||...:         :::|
  Fly   560 ------------------------MPRSAPVSPSHMDN----SRESSPLQDI---------VLQS 587

Zfish   290 EPSSRPSFSIE 300
            .|.| |..|:|
  Fly   588 APGS-PGMSLE 597

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
foxd3	NP_571365.2	Forkhead	96..182	CDD:278670	48/86 (56%)
FoxK	NP_001261701.1	FHA	<170..253	CDD:238017
FoxK	NP_001261701.1	Forkhead	453..540	CDD:278670	48/86 (56%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850