Protein Alignment sox17 and Sox15

DIOPT Version :10

• Sequence 1: NP_571362.2
• Gene: sox17 / 30544
• ZFINID: ZDB-GENE-991213-1
• Length: 413
• Species: Danio rerio
• Sequence 2: NP_523739.2
• Gene: Sox15 / 36575
• FlyBaseID: FBgn0005613
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 544
• Identity: 152/544 - (27%)
• Similarity: 207/544 - (38%)
• Gaps: 185/544 - (34%)

Zfish     1 MSSPDAGYSSDDPSQTSSCSS-----------------VMMPGMGQCPWVDPLSPL-SDSKSKHE 47
            :|.|.||.......|...|:|                 :..|   .|.:::...|| :|.|.:
  Fly   142 LSHPHAGMVGGGTGQMEDCTSHSPIEAASMWSYDYKGDLCAP---NCGYLERHKPLPADLKYR-- 201

Zfish    48 KCSAAGPG----RGKSEPRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALPMVD 108
                  ||    :...|.||||||||||||||.|||:||.:|||||||:|||||||.|::|...|
  Fly   202 ------PGGTQSKSAKESRIRRPMNAFMVWAKIERKKLADENPDLHNADLSKMLGKKWRSLTPQD 260

Zfish   109 KRPFVEEAERLRVKHMQDHPNYKYRPRRRKQVK------RNKRLEPSFPLPGMCDAKMT--LCTE 165
            :||:|||||||||.||.:|||||||||||||.|      ..|....|.|.||...:|..  |.|.
  Fly   261 RRPYVEEAERLRVIHMTEHPNYKYRPRRRKQSKLRAMQPGGKEQSESSPNPGTGGSKSNPKLATP 325

Zfish   166 GMSAGYSGAGLP---QYC----ENH------TLFESYSLPTPDPSPMD----AGTTEFFAQL--- 210
            .::...|....|   ..|    :||      .|:|....||..||.:|    |.:||....|
  Fly   326 PLATASSSYTTPTDESTCNSTNQNHGQSTPGGLYEQPLKPTYSPSSVDCYSNADSTEQIESLAAN 390

Zfish   211 -------------------------------------QDQSAFSYHHQQ--EHHFQEQTNILNDT 236
                                                 |::.|.|....:  :...|.|..|...|
  Fly   391 CPPALLNESSPTGGGYDNSLLLKKLTKPSPSRAAKSRQEKLAKSEEKNKGSQSQGQSQQGIYAAT 455

Zfish   237 H-----------CHGNTQTLKSR----QSHSIA---YSNINTNTNSNLHAPINAQLSSINLQQVF 283
            :           ..|...|..:|    ..||:.   |..::.:.:.|..:..|: :|:  |||
  Fly   456 YPLAPTSVAVVAARGMYVTCNNRGLLDHGHSVKGTFYPPVSVSEDDNSTSMRNS-ISA--LQQ-- 515

Zfish   284 HENANPQISHHPGTHLNIFNRSPSSS---------SHHAMTPAYLNCPSTLDTFYNSSS------ 333
                          |.|:...:||||         |.:.::.|. || ..|....|..|
  Fly   516 --------------HCNVVTSTPSSSGGTMPTSEMSSYTVSMAD-NC-GNLRLSMNELSGNEYLP 564

Zfish   334 ---------------QMKELSHCVSSHTHKQQSIAEAQSQASTATHSSGQMVDEVEFEHCLSFGV 383
                           |..::.:..|:..||:.:...|..|.......:.|..|:.|.|     ..
  Fly   565 SANAYGMQYEDFLRYQSNDMDYSTSAVEHKETTSDSASGQKCLKYPDTNQNYDDYEAE-----AY 624

Zfish   384 PSAPLPGSDLISTVLSDASSAVYY 407
            .:|.||           |::|.||
  Fly   625 SNAMLP-----------ATAASYY 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sox17	NP_571362.2	HMG-box_SoxF_SOX17	57..137	CDD:438850	59/79 (75%)
		Sox17_18_mid	<186..225	CDD:463454	13/84 (15%)
Sox15	NP_523739.2	HMG-box_SoxF	214..289	CDD:438841	58/74 (78%)
		PHA03273	305..>391	CDD:223031	23/85 (27%)