DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment myod1 and nau

DIOPT Version :9

Sequence 1:	NP_571337.2	Gene:	myod1 / 30513	ZFINID:	ZDB-GENE-980526-561	Length:	275	Species:	Danio rerio
Sequence 2:	NP_476650.1	Gene:	nau / 42799	FlyBaseID:	FBgn0002922	Length:	332	Species:	Drosophila melanogaster

Alignment Length:	232	Identity:	96/232 - (41%)
Similarity:	123/232 - (53%)	Gaps:	45/232 - (19%)

- Green bases have known domain annotations that are detailed below.

Zfish    46 DEHHHI-EDEHVRAP---SGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNDAFET 106
            ||:..: .:|||.||   |....:..||.|||||||:|:...||||||||||||||.|||:|||.
  Fly   119 DENSSLSSEEHVLAPLVCSSAQSSRPCLTWACKACKKKSVTVDRRKAATMRERRRLRKVNEAFEI 183

Zfish   107 LKRCTSTNPNQRLPKVEILRNAISYIESLQALLRSQEDNYYPVLEHYSGDSDASSPRSNCSDGMM 171
            |||.||:||||||||||||||||.|||||:.||:....         :.|.|..:|
  Fly   184 LKRRTSSNPNQRLPKVEILRNAIEYIESLEDLLQESST---------TRDGDNLAP--------- 230

Zfish   172 DFMGPTCQTRRRNSYDSSYFNDTPN------------ADARNNKNSVVSSLDCLSSIVERISTET 224
            ...|.:||:...:||..:|..|..:            .|...|.|.  ||||||:.||:.|:..|
  Fly   231 SLSGKSCQSDYLSSYAGAYLEDKLSFYNKHMEKYGQFTDFDGNANG--SSLDCLNLIVQSINKST 293

Zfish   225 PACPVLSVPEGHEESPCSPHEGSVLSDTGTTAPSPTS 261
            .: |:        ::..:|......|...:.|.:|||
  Fly   294 TS-PI--------QNKATPSASDTQSPPSSGATAPTS 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
myod1	NP_571337.2	BASIC	1..89	CDD:128794	22/46 (48%)
		HLH	85..136	CDD:278439	44/50 (88%)
		Myf5	151..220	CDD:289036	21/80 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	234..275		6/28 (21%)
nau	NP_476650.1	Basic	89..166	CDD:299793	22/46 (48%)
nau	NP_476650.1	HLH	162..213	CDD:278439	44/50 (88%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595014
Domainoid	1	1.000	89	1.000	Domainoid score	I7839
eggNOG	1	0.900	-	-		E1_KOG3960
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4470
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000989
OrthoInspector	1	1.000	-	-		otm26233
orthoMCL	1	0.900	-	-		OOG6_110195
Panther	1	1.100	-	-	O	PTHR11534
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2661
SonicParanoid	1	1.000	-	-		X581
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.780