DRSC/TRiP Functional Genomics Resources

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Protein Alignment Igsf9 and DIP-epsilon

DIOPT Version :9

Sequence 1:NP_001100667.1 Gene:Igsf9 / 304982 RGDID:1304566 Length:1179 Species:Rattus norvegicus
Sequence 2:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster


Alignment Length:518 Identity:108/518 - (20%)
Similarity:177/518 - (34%) Gaps:139/518 - (26%)


- Green bases have known domain annotations that are detailed below.


  Rat     4 CLRLTILSLILSQGADGR--------------RKPEVVSVVGR----AGESAVLGCDLLPPAGRP 50
            ||..:.::|....|::|.              ..||...|:..    ||.:..|.|.:.....  
  Fly    18 CLIASSVALSTDTGSEGNAGNVGGSTLNNVISEDPEFTDVIENITVPAGRNVKLACSVKNLGS-- 80

  Rat    51 PLHVIEWLRF--GFLLPIFIQFGLYSPRIDPDYVGRVRLQTGASLQIEGLRVEDQGWYECRVLFL 113
              :.:.|:.|  ..:|.:.......:|||...:....:.:|. .|.|..::.||:|.|.|::..:
  Fly    81 --YKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTW-FLHINNVQEEDRGRYMCQINTV 142

  Rat   114 DQHSPEQDFANGSWVHLTVNSPPQFQE--TPPLVLEVKELEAVTLRCVALGSPQPYVTWKFRGQD 176
            .        |...:..:.|..||...:  |...:: |:|.:.|||||.|.|||:|.:.||     
  Fly   143 T--------AKTQYGFVKVVVPPNIDDALTSSDII-VREGDNVTLRCKAKGSPEPTIKWK----- 193

  Rat   177 LGKGQGQVQVRNGTLWI----------RRVERGSAGDYTCQASS-TEGSVTHTTQLLVLGPPVIV 230
              :..|...|.|.||.:          .|:.|...|.|.|.||: ...||:...::.|...|::.
  Fly   194 --RDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPMVW 256

  Rat   231 VPPNNNTVNASQDVSLACRAEAYPANLTYSWFQDRIN-VFHISRLQSRVRILVDGSLWLQAT--- 291
            :|.....:....:::|.|..||.|.:|.| |.::... :...|:.::..   :.|....:||   
  Fly   257 IPHQLVGIPIGFNITLECFIEANPTSLNY-WTRENDQMITESSKYKTET---IPGHPSYKATMRL 317

  Rat   292 -----QPDDAGHYTCVPSNGFPHPPSASAYLTVLYPAQVTVMPPETPLPIGMRGVIRCPVRANPP 351
                 |..|.|:|.||..|                        |...:...::..:..|....||
  Fly   318 TITNVQSSDYGNYKCVAKN------------------------PRGDMDGNIKLYMSSPPTTQPP 358

  Rat   352 LLFVTWTKDGQALQLDKFPGWSLGPEGSLVIALGNEDALGEYSCTPY--NSLGTAGSSPVTRVLL 414
            ....|..:                     ......|.||..|..||.  |.:|..|..|...|:.
  Fly   359 PTTTTLRR---------------------TTTTAAEIALDGYINTPLNGNGIGIVGEGPTNSVIA 402

  Rat   415 KAPPAF--------IDQPKEEYFQEVGRDLLIPCSARGDPPPIVSWAKVGR--GLQGQAQVDS 467
            ....:.        ||:.|::              ..|..|....|:| |:  |..|.....|
  Fly   403 SGKSSIKYLSNLNEIDKSKQK--------------LTGSSPKGFDWSK-GKSSGSHGNLMASS 450

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Igsf9NP_001100667.1 IG 28..110 CDD:214652 19/87 (22%)
Ig strand A 136..139 CDD:409353 1/2 (50%)
IG_like 143..223 CDD:214653 28/90 (31%)
Ig strand A' 145..148 CDD:409353 0/2 (0%)
Ig strand B 154..161 CDD:409353 5/6 (83%)
Ig strand C 167..172 CDD:409353 1/4 (25%)
Ig strand C' 175..177 CDD:409353 0/1 (0%)
Ig strand D 183..187 CDD:409353 0/3 (0%)
Ig strand E 189..193 CDD:409353 2/3 (67%)
Ig strand F 202..210 CDD:409353 4/7 (57%)
Ig strand G 213..223 CDD:409353 2/9 (22%)
Ig_3 226..305 CDD:404760 20/87 (23%)
putative Ig strand A 226..230 CDD:409353 1/3 (33%)
putative Ig strand A' 235..239 CDD:409353 0/3 (0%)
putative Ig strand B 241..251 CDD:409353 2/9 (22%)
putative Ig strand C' 267..270 CDD:409353 0/3 (0%)
putative Ig strand D 279..282 CDD:409353 0/2 (0%)
putative Ig strand E 284..290 CDD:409353 1/5 (20%)
putative Ig strand F 297..305 CDD:409353 4/7 (57%)
putative Ig strand G 310..319 CDD:409353 0/8 (0%)
Ig 322..407 CDD:416386 14/86 (16%)
Ig strand A' 324..328 CDD:409353 0/3 (0%)
Ig strand B 333..347 CDD:409353 1/13 (8%)
Ig strand C 353..359 CDD:409353 1/5 (20%)
Ig strand C' 362..364 CDD:409353 0/1 (0%)
Ig strand D 371..374 CDD:409353 0/2 (0%)
Ig strand E 378..382 CDD:409353 0/3 (0%)
Ig strand F 391..399 CDD:409353 3/9 (33%)
Ig 418..503 CDD:416386 11/60 (18%)
Ig strand A 418..421 CDD:409353 0/10 (0%)
Ig strand A' 427..430 CDD:409353 0/2 (0%)
Ig strand B 436..443 CDD:409353 0/6 (0%)
Ig strand C 449..454 CDD:409353 1/4 (25%)
Ig strand C' 457..459 CDD:409353 0/3 (0%)
Ig strand D 462..466 CDD:409353 0/3 (0%)
Ig strand E 469..473 CDD:409353
Ig strand F 482..490 CDD:409353
Ig strand G 493..503 CDD:409353
FN3 508..599 CDD:238020
FN3 625..715 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 766..807
PHA03247 <777..1062 CDD:223021
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 819..846
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 869..895
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 942..979
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1016..1079
PDZ-binding. /evidence=ECO:0000250 1177..1179
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 20/108 (19%)
Ig 69..139 CDD:143165 16/74 (22%)
IG_like 165..249 CDD:214653 28/91 (31%)
IGc2 172..237 CDD:197706 25/71 (35%)
IG_like 267..348 CDD:214653 20/108 (19%)
Ig 270..339 CDD:299845 20/96 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.000

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