DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment serpinh1b and Spn42Dd

DIOPT Version :9

Sequence 1:	NP_001296752.1	Gene:	serpinh1b / 30449	ZFINID:	ZDB-GENE-990415-93	Length:	405	Species:	Danio rerio
Sequence 2:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	384	Identity:	110/384 - (28%)
Similarity:	187/384 - (48%)	Gaps:	37/384 - (9%)

- Green bases have known domain annotations that are detailed below.

Zfish    28 TSMADTSANLAFNLYHNVAKEKGLENILISPVVVASSLGMVAMGSKSSTASQVKSVLKADALKDE 92
            ||:|..::.   .:|..::|....:|:::|||.:.:.|.||.||::.|||.:::|.|...:...|
  Fly    11 TSVACQTSK---EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKE 72

Zfish    93 HLHTGLSELLTEVSDPQTRNVTWKISNRLYGPSSVSFAEDFVKNSKKHYNYEHSKINFRDKRSAI 157
            .:......||.::.. |......|::||:|.....|..:::....::.:..|...|:..:...|.
  Fly    73 AVAARYGALLNDLQG-QEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAA 136

Zfish   158 NSINEWAAKTTDGKLP------EITKDVKNTDGAMIVNAMFFKPHWDEKFHHKMVDNRGFLVTRS 216
            ..||:|....|.||:.      .:|.|||    |::|||::||..|:.||.........|.||.:
  Fly   137 ERINQWVLDQTSGKIKGMIDPGSMTSDVK----ALLVNAIYFKGQWESKFDPAKTRASTFQVTAN 197

Zfish   217 HTVSVPMMHRTGIY--GFYEDTENRFLIVSMPLAHKKSSMIFIMPYHVEPLDRLENLLTRQQLDT 279
            .:|.|.||.:.|.:  .::.|.:.:  ::.:|..:...||...:|..||.|..||     :::..
  Fly   198 KSVPVQMMAQMGTFRANYFRDLDAQ--VIELPYLNSNLSMTIFLPREVEGLSALE-----EKIVG 255

Zfish   280 WISKLEERAVAISLPKVSMEVSHDLQKHLGELGLTEA-VDKSKADLSNI----SGKKDLYLSNVF 339
            :...|..:.|.:.|||..:|...:|::.|.:||:.|. .|||  |||.:    ||.|   :|.|.
  Fly   256 FARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKS--DLSGLFADKSGGK---VSQVS 315

Zfish   340 HASSLEWDTEGNPF--DPSIFGSEKMRNPKLFYADHPFIFLVKDNKTNSILFIGRLVRP 396
            |.:.||.:.||...  ..|:..:.:........|||||.|:::|  .|:|.|.||:|.|
  Fly   316 HKAFLEVNEEGAEAAGATSVAVTNRAGFSTFLMADHPFAFVIRD--ANTIYFQGRVVSP 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
serpinh1b	NP_001296752.1	hsp47	28..393	CDD:239001	107/379 (28%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	104/374 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920