Protein Alignment brd2a and tbrd-2

DIOPT Version :9

• Sequence 1: NP_571275.2
• Gene: brd2a / 30445
• ZFINID: ZDB-GENE-990415-248
• Length: 836
• Species: Danio rerio
• Sequence 2: NP_611401.2
• Gene: tbrd-2 / 37207
• FlyBaseID: FBgn0034423
• Length: 674
• Species: Drosophila melanogaster
• Alignment Length: 865
• Identity: 174/865 - (20%)
• Similarity: 296/865 - (34%)
• Gaps: 283/865 - (32%)

Zfish    35 RIRKPSLLYEGFEGPALPHIAQSGPPQPAVRDPSRQGRMTNQLQFLQKALVKTLWRHHFAWPFHE 99
            :::.|:.:...|    :||             |...||.||:|.:.:|.|:....:..:|..|.|
  Fly    10 KLKLPNRVQPEF----IPH-------------PGMAGRYTNKLHYFKKHLLDEARKKKYALDFLE 57

Zfish   100 PVDAAKLNLPDYYNIIKQPMDMGTIKKRLENNYYRSASECMQDFNTMFTNCYIYNKPTDDIVLMA 164
            |||...|.:|.||.:|.:|||:|||.||::||||:|.:|.:.||..:.:||:::|:..|.:....
  Fly    58 PVDTEALMVPTYYTVIHRPMDIGTIVKRVQNNYYKSVNEAIADFKQIISNCFLFNRSGDVVYRKG 122

Zfish   165 QSLEKAFLQKVAQMPEVEE----EIPAPVPRGKQSKPKKGQKLFSGGITTAHQVPAISSLSQLAY 225
            |.|||.|.:|:..||...|    ..|..|.|.:.:.|...|       |.......:..|..:
  Fly   123 QMLEKFFHKKLRGMPSGPEVPCNRDPKAVGRPRTNAPSSAQ-------TERKCRELLKKLQSI-- 178

Zfish   226 SPPTPDTPDSVLSTPPQTLITKNFPPPPLHSTPALLGLPPTQPTAKKKGVKRKADTTTPTTTVMP 290
                         |.....:|:||                  .:.|...:::|.|... ..:|..
  Fly   179 -------------TNQTDAMTRNF------------------FSNKWDSLQKKVDRQY-FKSVNE 211

Zfish   291 LTLGVGG----------------MGMGMGMGMSMGMGMGMGLGGDSPLTLSNMGMDSKQSLS--- 336
            ..|.|.|                .........||        .|:|.|..:....|..:.|:
  Fly   212 FCLHVDGCFRKYHEPAKILYERVFNQPAAWCTSM--------NGNSSLESALNAADLNELLAAAK 268

Zfish   337 LSLGMSLE-DKVPARRGGSGRPIKPPRKDLPDSQNQHQPVRRGKLSQQLRYCSTILKELLSKKHT 400
            |::...:: .::|    |||.|:  ..|.|.::                 :|.| |.::::|...
  Fly   269 LTVNSLMQCVQMP----GSGEPL--TAKSLVET-----------------FCDT-LNKMINKMEA 309

Zfish   401 AYAWPFYKPVDVSSLGLHDYYDIIMYPMDLSTIKRKMDHREYRDALQ--FAADVRLMFSN----- 458
            ...                     ..|...|:.::||...:..|.:|  |...:.|:..|
  Fly   310 GQR---------------------NSPNPSSSKRQKMSPEQETDLVQGEFKPAMELLSGNEIDNL 353

Zfish   459 -CYKYNPPDHDVVAMARRLQD----VFEFRFAKMPD----------EPLESLPPASLGG------ 502
             .......|.:.:..:.|:.|    ..:..|||:|.          :.:|.....:.|.
  Fly   354 MAVSIESSDDEAIDASMRITDADRCATQKLFAKLPTNAMKEIIHMVQQIEGFSSENCGDLSFDVK 418

Zfish   503 GLGGDSSSSSSSSSSSSESDVSSESESESSPSSDSEEERAHRLAQLQEQVCTQLRAVHEQLAALS 567
            ||..|:.....|:.:.:....|.....:..||.....:||     ||.|:....|.:::
  Fly   419 GLATDTMIMMKSAVTKATRAHSKLKLKDMQPSEKEGLQRA-----LQSQLVNITRMLNK------ 472

Zfish   568 STPIIKPKKKKEKKDKKKKKKPEKHKRSRSVIEDEVVMRPAKIPKLPKTPKSRSNSKAATSTQSK 632
                           .:::..|..:.|:::...:.||.:.|..|...|....::|..|.......
  Fly   473 ---------------NRRRCGPLINFRNKNNTANNVVRKRATAPLTAKLKPLQANVMAPQLGAGV 522

Zfish   633 KSSNKKSNKSKSSKKAQPTFFPPPLSHSGLTPHYDSEEEEETSPMSYDEKRQLSLDINRLPGEKL 697
            ..::..|:.|.....|     |..||..|.||                   ..:|.||
  Fly   523 VETHNLSDTSDDDVSA-----PVKLSAIGGTP-------------------MRNLPIN------- 556

Zfish   698 GRVVHIIQSREPSLRDTNPEEIEIDFETLKPSTLRELERYVMMCLRKKPRKPFVAIKGSAGKSRE 762
                            :||.:                    |..:|..|:.|.|.
  Fly   557 ----------------SNPLQ--------------------MQPIRSPPKLPHVV---------- 575

Zfish   763 ELALEKKRELERRLQDVSGQLNSVKKPQKTKAEKPSAVEPHAVASRLSASSSSSDS--------- 818
            ||.:......|..::..||:|:.    .::::...:.:.|.:.:|..|.|:|||.|
  Fly   576 ELQMSSSSSSESEMKSKSGRLSR----SRSRSMSDTKLRPRSNSSASSRSNSSSSSGSNAGSSSG 636

Zfish   819 ----SSSSSSSSSSDTSESD 834
                |||||||||:::|||:
  Fly   637 SRSRSSSSSSSSSNNSSESN 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brd2a	NP_571275.2	Bromo_Brdt_I_like	72..178	CDD:99929	43/105 (41%)
		Bromo_Brdt_II_like	383..484	CDD:99930	16/112 (14%)
		BET	676..738	CDD:293640	5/61 (8%)
tbrd-2	NP_611401.2	Bromo_gcn5_like	34..136	CDD:99941	40/101 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	149	1.000	Inparanoid score	I4352
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.910