DRSC/TRiP Functional Genomics Resources

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Protein Alignment fzd7a and Corin

DIOPT Version :9

Sequence 1:NP_571214.2 Gene:fzd7a / 30369 ZFINID:ZDB-GENE-990415-223 Length:559 Species:Danio rerio
Sequence 2:NP_610297.2 Gene:Corin / 35691 FlyBaseID:FBgn0033192 Length:1397 Species:Drosophila melanogaster


Alignment Length:237 Identity:65/237 - (27%)
Similarity:94/237 - (39%) Gaps:32/237 - (13%)


- Green bases have known domain annotations that are detailed below.


Zfish     2 AFLKMQHCCGITRYFLLLFTVAL--QTTSGQYHGEKGISI---PEHGFCQPISIPLC--TDIAYN 59
            ||..:....|:..||....|:..  :|.....|.|...|.   |..|.|.||.:..|  ..|.||
  Fly   731 AFALLAIAGGLAAYFNAYPTIKFVNKTIINTIHVEDTTSFGKNPAPGTCLPIIVRFCQGPQIPYN 795

Zfish    60 QTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSMDLKFFLCSMYAPVCTVLEQAIPPCRSLCERAR 124
            .|:.||.:||..|.:...::..:..||.|:|...:..|||:::.|.|......:|||::||....
  Fly   796 YTVFPNYIGHFGQLETQTDLDSYEALVDVRCYELVSLFLCTLFVPKCGQSGATVPPCKTLCTETM 860

Zfish   125 QGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDAGSPTSNPTPYVPELITLQPNLVVRP 189
            :.|....:.||...||.|.|:.|....:.|.|||.:.             |.|::    .....|
  Fly   861 RRCGFFFDVFGLSLPEYLNCKLFKDFPSSEDCVGLDE-------------VREVM----RAATHP 908

Zfish   190 N-QQFTCPLQLKVPTYLKYHFMGEKDC-----GAPCEPTRPN 225
            . ..|.|.....:|.  :|...|..||     .|.||...|:
  Fly   909 KCDGFQCDQNRCLPQ--EYVCDGHLDCMDQADEAKCERCGPD 948

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fzd7aNP_571214.2 CRD_FZ 41..163 CDD:382974 40/123 (33%)
7tm_GPCRs 228..558 CDD:391938
TM helix 1 238..262 CDD:341315
TM helix 2 271..292 CDD:341315
TM helix 3 322..344 CDD:341315
TM helix 4 365..381 CDD:341315
TM helix 5 403..426 CDD:341315
TM helix 6 454..479 CDD:341315
TM helix 7 508..533 CDD:341315
CorinNP_610297.2 CRD_FZ 778..894 CDD:143549 37/115 (32%)
LDLa 911..942 CDD:238060 8/32 (25%)
LDLa 945..979 CDD:238060 1/4 (25%)
SR 980..>1034 CDD:214555
SRCR 992..1086 CDD:278931
Tryp_SPc 1103..1343 CDD:214473
Tryp_SPc 1104..1346 CDD:238113
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3577
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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