Protein Alignment Rnf43 and rnf43

DIOPT Version :10

• Sequence 1: XP_006247152.1
• Gene: Rnf43 / 303412
• RGDID: 1305204
• Length: 802
• Species: Rattus norvegicus
• Sequence 2: XP_002935238.2
• Gene: rnf43 / 100491274
• XenbaseID: XB-GENE-952685
• Length: 689
• Species: Xenopus tropicalis
• Alignment Length: 790
• Identity: 305/790 - (38%)
• Similarity: 411/790 - (52%)
• Gaps: 178/790 - (22%)

  Rat     6 QLQLAVLWPWLLMATLHAGFGHTGLVLAAAVESERSAEQKAIIRVIPLKMDPTGKL---NLTLEG 67
            :||||.|| .||..||.|       |.:|...:||..:.||:|||.||:.:.:|.:   ||||||
 Frog     5 RLQLASLW-LLLTVTLQA-------VASAMGTTEREMDVKALIRVTPLQAEESGGVGQGNLTLEG 61

  Rat    68 VFAGVAEVSPAEGKLMQSHPLYLCNASDDDNLEPGFISIVKLESPRRAPRPCLSLASKARMAGER 132
            :||.|||:|||||:|:|.|||.|||.|:||..:||||||||||:|.|..:||||||:|||:||||
 Frog    62 LFARVAEISPAEGRLLQFHPLSLCNTSEDDQTKPGFISIVKLETPDRDTQPCLSLANKARLAGER 126

  Rat   133 GASAVLFDITEDRSAAEQLQQPLGLTKPVVLIWGSDAEKLMEFVYKNRKAYVWIELKEPPAWANY 197
            ||.|||||||.||.|.:|||||.|:.:|||||||.||||||:.|.||::|.|.||::|.|.|.::
 Frog   127 GAHAVLFDITNDRGALQQLQQPAGINQPVVLIWGPDAEKLMDVVNKNKEALVKIEVQEQPKWLHH 191

  Rat   198 DVWILLTVVGTVFVIILASVLRIRCRPHPSRPDPLQQRTARAISQLATRRYQASC---RRARAEW 259
            |:||||||.|||...:|.:|.|:.||..|.: |.:||:|..|||:|.|||||...   :||...|
 Frog   192 DIWILLTVAGTVMFFVLYAVARLLCRQPPPQ-DSIQQQTLLAISRLGTRRYQQRMLKDQRASGGW 255

  Rat   260 PDSGSSSSSAPVCAICLEEFTEGQELRVISCLHEFHRTCVDPWLHQHRTCPLCMFNIVEGDSFSQ 324
            .::.|:|||.|||||||||||:|||||::.|.||:|..||||||.|:.||||||::|::.
 Frog   256 VETASTSSSVPVCAICLEEFTDGQELRILPCCHEYHLGCVDPWLRQNHTCPLCMYDILDS----- 315

  Rat   325 ALGASP---SYQEPGRRLHLIRQHPGHAHY--HLP--SAYLLGPSRNSVAQTPRPRPFLPSQEPS 382
              |..|   :::.|. :..|..::||.|..  |||  ...::.|:.|:....||...:|..
 Frog   316 --GTPPRPLAHRAPS-QTQLWGRYPGSARLMSHLPPHGTPMVFPTPNNSLFLPRAPYYLDH---- 373

  Rat   383 MGSRHQRLPR------ASHLRAPEEQQHLAVSPGHPYAQGWGPNRLRCTSQHPNACPVALRRARP 441
              :.|.::|.      .:|.|..|..:.|.:|||
 Frog   374 --THHWQMPEQMAMQMRTHRRGAEGTRELGISPG------------------------------- 405

  Rat   442 HESSGSGESYCTERSGYLADGPASDSSSGPCHGSSSDSVVNCTDISLQGVHG-SSSTFRSSLSSD 505
                      |.:.||||.|.|.|||||||||||||:   |||||||..:|| |||:..||.|:.
 Frog   406 ----------CQDSSGYLPDDPGSDSSSGPCHGSSSE---NCTDISLHCLHGTSSSSVHSSQSNQ 457

  Rat   506 FD---PLV--YCSPEGALQGKEVQPSMTSRPRSLDSVVPTGETQVS--SHIHYHRHRHHHYKKQF 563
            .|   |.:  |..|:|.|      |::.          |...||.|  ||:|:|:||||||::
 Frog   458 EDSSPPALASYLLPQGEL------PALN----------PLLSTQASYASHVHFHQHRHHHYRR-- 504

  Rat   564 QWHSRKPGLETGVP-QSRPAASHTQLEPSL--PDQQLTTPNPAVSSML----PNPQRPRALTEP- 620
                .:|.:....| :|:.....::.:||.  ..:..|..|..:.|::    |.|...|...:|
 Frog   505 ----NQPSMSHSHPHRSKRRTKVSRADPSYYREHRHTTGANGELRSLMVRREPRPSCSRTCFDPR 565

  Rat   621 -----------APGLAEAVSPSPSPN-PSLLNLQKSNLPVRYPQRKRRGGPSEALPTSQPQDLTV 673
                       .|..|..|..|..|: .:.|...:::.|.|..::|:...||.
 Frog   566 TNREHPRHQQSMPQAASVVQGSSEPDVATSLRGSRTDPPSRTYRKKKSSAPSH------------ 618

  Rat   674 HTACPVPPHYSPSLAYP-------------WPPEVHPLIFRPPGLDRRLLHDVPGPCYSSSQPVW 725
                 :|..|||...:|             |..||            ||||........::..:.
 Frog   619 -----LPLLYSPRHCHPANSVQMSESSHPRWAEEV------------RLLHSRVNSHRENTAMMH 666

  Rat   726 LYLNPRQPLG 735
            ||..|....|
 Frog   667 LYHPPHHNQG 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rnf43	XP_006247152.1	ZNRF_3_ecto	85..187	CDD:408039	70/101 (69%)
		RING-H2_RNF43	269..319	CDD:438451	34/49 (69%)
		dnaA	598..>743	CDD:455861	34/168 (20%)
rnf43	XP_002935238.2	ZNRF_3_ecto	80..182	CDD:408039	71/101 (70%)
		HRD1	<244..366	CDD:227568	53/129 (41%)
		RING-H2_RNF43-like	267..311	CDD:438328	32/43 (74%)
		DUF4573	523..643	CDD:434493	25/136 (18%)