DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment hoxb4a and Scr

DIOPT Version :9

Sequence 1:	NP_571193.1	Gene:	hoxb4a / 30340	ZFINID:	ZDB-GENE-990415-105	Length:	246	Species:	Danio rerio
Sequence 2:	NP_001368995.1	Gene:	Scr / 40833	FlyBaseID:	FBgn0003339	Length:	564	Species:	Drosophila melanogaster

Alignment Length:	166	Identity:	77/166 - (46%)
Similarity:	98/166 - (59%)	Gaps:	30/166 - (18%)

- Green bases have known domain annotations that are detailed below.

Zfish    53 HQRSGCADPPYSSCQGPGQPAAVISPRGHVLPTTALSTPLPEP-SHHCDSVTPSPPPACGQTPTS 116
            |..||.:.       |||.                ::.|:..| ....||.:.|.    .:..:|
  Fly   254 HSGSGVSG-------GPGN----------------VNVPMHSPGGGDSDSESDSG----NEAGSS 291

Zfish   117 QNTSTVSSRKDPVVYPWMKKVHVNIVSPNYSGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRR 181
            ||:.. ..:..|.:|||||:||:...:.| :.||.||.||:|||.|.||||||||:|||||||||
  Fly   292 QNSGN-GKKNPPQIYPWMKRVHLGTSTVN-ANGETKRQRTSYTRYQTLELEKEFHFNRYLTRRRR 354

Zfish   182 VEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKI 217
            :||||.|||:|||||||||||||||||:||:.:..|
  Fly   355 IEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNI 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hoxb4a	NP_571193.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..125		14/72 (19%)
		Antp-type hexapeptide	130..135		3/4 (75%)
		Homeobox	154..207	CDD:278475	44/52 (85%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	210..246		3/8 (38%)
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	45/52 (87%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45771
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.910