DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hoxa2b and Antp

DIOPT Version :9

Sequence 1:	NP_571181.1	Gene:	hoxa2b / 30325	ZFINID:	ZDB-GENE-990415-98	Length:	363	Species:	Danio rerio
Sequence 2:	NP_996167.1	Gene:	Antp / 40835	FlyBaseID:	FBgn0260642	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	194	Identity:	71/194 - (36%)
Similarity:	90/194 - (46%)	Gaps:	66/194 - (34%)

- Green bases have known domain annotations that are detailed below.

Zfish    26 PPVGDAFQSSSIKSSTLSHSTLIPPPFEQTIPSLNPGSHP-RHSRPKQNPNGSCPLPAASLP-PE 88
            ||||...|.       :.|....||...|        .|| :|:.|.||||..    ::.:| |.
  Fly   238 PPVGAPPQG-------MMHQGQGPPQMHQ--------GHPGQHTPPSQNPNSQ----SSGMPSPL 283

Zfish    89 YPWMKEK--KASKKNQTTSTAATTDPGPLYFSPQGSPEISDGGSGATRRLRTAYTNTQLLELEKE 151
            ||||:.:  |..::                                 :|.|..||..|.||||||
  Fly   284 YPWMRSQFGKCQER---------------------------------KRGRQTYTRYQTLELEKE 315

Zfish   152 FHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENHHGDGKPPSLEEAGGRGD 215
            ||||:||.|.||:|||..|.|||||:|:||||||||.|::.:.|      |:|.|    ||.||
  Fly   316 FHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKENKTK------GEPGS----GGEGD 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hoxa2b	NP_571181.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..132		19/93 (20%)
		Antp-type hexapeptide	88..93		3/4 (75%)
		Homeobox	137..189	CDD:278475	37/51 (73%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	186..218		11/30 (37%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	245..279
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	27/119 (23%)
Antp	NP_996167.1	Homeobox	301..354	CDD:395001	37/52 (71%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810