DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Slc36a3 and CG32081

DIOPT Version :9

Sequence 1:	NP_001019935.1	Gene:	Slc36a3 / 303148	RGDID:	1309092	Length:	477	Species:	Rattus norvegicus
Sequence 2:	NP_729646.1	Gene:	CG32081 / 326194	FlyBaseID:	FBgn0052081	Length:	471	Species:	Drosophila melanogaster

Alignment Length:	445	Identity:	130/445 - (29%)
Similarity:	219/445 - (49%)	Gaps:	53/445 - (11%)

- Green bases have known domain annotations that are detailed below.

  Rat    44 RRKADALMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHL 108
            |..|..:..|..|..|||..:|||.:.:||:...||::.|.:.|:::..:.:|.|.:|:.|....
  Fly    13 RNVAHPISDIGAFFSLLKCVVGTGVMAIPLSFNYAGIVTGIILLVSVCFMLIHGMQMLIICMIEC 77

  Rat   109 TSRLQRSFVNYEETTMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFMADNLQQIV 173
            :.|:|..:..|....:||.:..|. :.:..|..|||:|..:|..:|.|.|.||.:|:|..|:|:|
  Fly    78 SRRMQIGYATYPVAMVYSFDQGPR-FFKYISKAGRYIVDGVLAFSQFGVCVVYNVFVAATLKQLV 141

  Rat   174 EEAHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLILLVLVQNPQVLSIFSTLATITTLSSLALI 238
            :               ....:.|.|.|:..|...||....::..:.|..|:.||:|...:..:|:
  Fly   142 D---------------FYWVVADLRIYIAVIALCLIPPFQIRKLKYLVPFNILASILIYTGFSLM 191

  Rat   239 FEYL-IQIPHHSHLPLVASWKTFL--------LFFGTAIFTFEGVGMVLPLKSQMKSPQQFPAVL 294
            ..|| :.:|     |:..  :..|        ||||.|:|:...||::|.:::.|..|:.
  Fly   192 MYYLFVDLP-----PITE--RNILFGRIDKIPLFFGIALFSITSVGVMLAVEATMAKPRH----- 244

  Rat   295 YLG--------MSFVIFLYICLGTLGYMKFGADTQASITLNLP-NCWLYQSVKLMYSVGIFFTYA 350
            |||        :..||..|:..|.:||.::|.:|..||:||:| :..|.|..|...:..||.||.
  Fly   245 YLGWFGILDRAILLVIISYVTFGLMGYWRYGDETAGSISLNIPTDEVLSQVAKGFIAAAIFLTYP 309

  Rat   351 LQFHVPAEIIVPYVVSRASE--NWALFIDLTVRAALVCLTCFSAVLIPRLDLVISLVGSVSSSAL 413
            |...|..:||:.:..::..:  |.|| .:..:||..|.|.|.:|::.|.|..::||||:::.|.|
  Fly   310 LAGFVIIDIIMNHFWNKNGDLPNAAL-KESILRACTVVLICITAIIAPNLGPLLSLVGALTISLL 373

  Rat   414 ALIIPPLLEIATFYSENISC----TTIAKDIMISILGLLGCVLGTYQALYEMTQQ 464
            .|:.|.|:||..:|....:.    ..:.|||...|:|:|..|.||..::.:|..:
  Fly   374 NLVFPALIEICLYYPPEYNYGKLKWVLVKDIFYVIVGILILVQGTVFSIKDMISE 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Slc36a3	NP_001019935.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
Slc36a3	NP_001019935.1	SLC5-6-like_sbd	52..458	CDD:294310	127/429 (30%)
CG32081	NP_729646.1	SLC5-6-like_sbd	17..422	CDD:294310	127/433 (29%)
CG32081	NP_729646.1	SdaC	20..415	CDD:223884	124/423 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352621
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940