Protein Alignment HADHA and hadha

DIOPT Version :10

• Sequence 1: NP_000173.2
• Gene: HADHA / 3030
• HGNCID: 4801
• Length: 763
• Species: Homo sapiens
• Sequence 2: NP_989224.1
• Gene: hadha / 394832
• XenbaseID: XB-GENE-959219
• Length: 760
• Species: Xenopus tropicalis
• Alignment Length: 762
• Identity: 590/762 - (77%)
• Similarity: 678/762 - (88%)
• Gaps: 3/762 - (0%)

Human     1 MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLS 65
            |.|.|.:|:|:|...   ....||.||:.:.|||||||||:||.:|.||||||.|:|||||||||
 Frog     1 MAAARLVGVLARLGG---ANRTGYTCRHLSMSSALLTRTHVNYEIKDDVAVVRFNTPNSKVNTLS 62

Human    66 KELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKL 130
            |:|.:|||:|||||||:|.::||||||||||||||||||||:.:|||.|||||||||.|::..||
 Frog    63 KQLQTEFSDVMNEIWANDAVQSAVLISSKPGCFIAGADINMIESCKTSQEVTQLSQEGQKMFAKL 127

Human   131 EKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVP 195
            |||.||||||||||||||||||||:||||:||||:||||||||||||.|||||||||||:|||:|
 Frog   128 EKSPKPIVAAINGSCLGGGLEVAIACQYRVATKDKKTVLGTPEVLLGLLPGAGGTQRLPRMVGLP 192

Human   196 AALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKR 260
            .|.|||||||:|||||||:||||||||:|||||||.||:||||||||||:..|:|:|.||||.|:
 Frog   193 TAFDMMLTGRNIRADRAKRMGLVDQLVDPLGPGLKSPEDRTIEYLEEVAVDCARGIAKKKISLKK 257

Human   261 DKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQ 325
            :|||::|:|.|.|::||||||:||.||:||.||||||||||||||:||:||::||.:||||.|:|
 Frog   258 EKGLMQKVTDYVMSVPFVRQQIYKTVEKKVNKQTKGLYPAPLKIIEVVRTGLDQGQEAGYLAEAQ 322

Human   326 KFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILK 390
            |||||..|.|||||:|||||||:|||||||.|::.|:.|||||||||||||||||||||||||||
 Frog   323 KFGELGTTPESKALIGLYHGQVICKKNKFGTPERPVQKLAILGAGLMGAGIAQVSVDKGLKTILK 387

Human   391 DATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLK 455
            |.|:..|.||||||:||||||||||:|||||||||.|||||||||:|||.|||||||||||:.:|
 Frog   388 DTTVEGLGRGQQQVYKGLNDKVKKKSLTSFERDSIVSNLTGQLDYKGFETADMVIEAVFEDIRIK 452

Human   456 HRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKD 520
            |:||:|||||:|.||||||||||||||:|||.|||||||||||||||||||||||||||:|||||
 Frog   453 HKVLQEVEAVVPPHCIFASNTSALPISQIAAASKRPEKVIGMHYFSPVDKMQLLEIITTDKTSKD 517

Human   521 TSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAA 585
            |:|:|||||||||||||||||||||||||||.|||:||:|:|||||||||||:|:|.|||||||:
 Frog   518 TTAAAVAVGLKQGKVIIVVKDGPGFYTTRCLGPMMAEVVRVLQEGVDPKKLDALSTGFGFPVGAS 582

Human   586 TLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNS 650
            ||.||||:|||.||||||||.|||||||||.|||..||:||||||||||||||||:|||.:.:||
 Frog   583 TLADEVGIDVAAHVAEDLGKAFGERFGGGNIELLKAMVAKGFLGRKSGKGFYIYQQGVKNRSINS 647

Human   651 DMDSILASLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLG 715
            ..:.||...||..|.||||:||||.||||||||||||||||||||.|.|||||||||||||||||
 Frog   648 GTEEILEKFKLQAKPEVSSNEDIQLRLVTRFVNEAVMCLQEGILANPVEGDIGAVFGLGFPPCLG 712

Human   716 GPFRFVDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFY 762
            ||||:.|.:||::||::::|||:.||.||||||||.|||:.|:|||:
 Frog   713 GPFRYADAFGAKRIVEKMRKYESVYGSQFTPCQLLLDHASDPSKKFH 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HADHA	NP_000173.2	fa_ox_alpha_mit	27..762	CDD:131494	580/734 (79%)
hadha	NP_989224.1	fa_ox_alpha_mit	24..759	CDD:131494	580/734 (79%)