Protein Alignment HADHA and CG8778

DIOPT Version :10

• Sequence 1: NP_000173.2
• Gene: HADHA / 3030
• HGNCID: 4801
• Length: 763
• Species: Homo sapiens
• Sequence 2: NP_610805.1
• Gene: CG8778 / 36392
• FlyBaseID: FBgn0033761
• Length: 299
• Species: Drosophila melanogaster
• Alignment Length: 321
• Identity: 96/321 - (29%)
• Similarity: 156/321 - (48%)
• Gaps: 63/321 - (19%)

Human     1 MVACRAIGILSRFSAFRILRSRGYICRNFT-------GSSALLTRTHINYGVKGDVAVVRINSPN 58
            |:..||.| |:|..|..::.|     ||..       |:..|:.|..   |.:..::|:.:|.|.
  Fly     3 MLIKRASG-LARQLARPLVAS-----RNLASAAPYGDGTEVLVERLD---GARQGISVIGLNRPA 58

Human    59 SKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEA 123
            :| |:.|:.:...|::|:.:|...:..|..||.|..||.|.||||:..... .|.:|.|:..:|.
  Fly    59 AK-NSFSRGMVETFNDVLEDIKKDNGSRVVVLRSLSPGIFCAGADLKERKG-MTPEEATEFVKEL 121

Human   124 QRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRL 188
            :.::..:|:...|::||::|:.||||||:|::|..|.|..|.|  :|..|..|..:|||||||||
  Fly   122 RGLLIAIEQLPMPVIAAVDGAALGGGLEMALACDIRTAASDTK--MGLVETRLAIIPGAGGTQRL 184

Human   189 PKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPE------ERTIEYLEE----- 242
            |:::....|.:::.|.|......||.:|||:.:|       |..|      ::.::..||
  Fly   185 PRILSPALAKELIFTARVFNGAEAKDLGLVNHVV-------KQNETQDAAYQQALKLAEEILPNG 242

Human   243 -VAITFAKGLADK------------------KISPKRDKGLVEKLTAYAMTIPFVRQQVYK 284
             |.:..||...||                  ::.|.:|:  :|.|.|:|..    |:.|||
  Fly   243 PVGVRMAKLAIDKGMQVDLATGYSIEEICYSQVIPTKDR--LEGLAAFAEK----RKPVYK 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HADHA	NP_000173.2	fa_ox_alpha_mit	27..762	CDD:131494	88/295 (30%)
CG8778	NP_610805.1	crotonase-like	48..299	CDD:474030	82/267 (31%)