Protein Alignment HADHA and CG4594

DIOPT Version :10

• Sequence 1: NP_000173.2
• Gene: HADHA / 3030
• HGNCID: 4801
• Length: 763
• Species: Homo sapiens
• Sequence 2: NP_609323.1
• Gene: CG4594 / 34316
• FlyBaseID: FBgn0032161
• Length: 280
• Species: Drosophila melanogaster
• Alignment Length: 305
• Identity: 76/305 - (24%)
• Similarity: 127/305 - (41%)
• Gaps: 54/305 - (17%)

Human    14 SAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSP--NSKVNTLSKELHSEFSEVM 76
            |.|..|.:.|...| ...::..||...||  .|..:|.:.:|.|  ||:...|..:|.:..||:.
  Fly     4 SNFLRLMAHGAPSR-LMSTATKLTTVEIN--DKTGIATLTMNRPPVNSQNVQLLLDLQTSISEIE 65

Human    77 NEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAI 141
            |     ::.|..:|.|:....|.||.||..:.. ..::.:..:..|.|.:...|..:|.|..|||
  Fly    66 N-----NKSRGLILTSASSNVFSAGLDIFEMYN-TDVERLRTVWTELQNVWIALYGTTLPTAAAI 124

Human   142 NGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPG----AGGTQRLPKMVGVPAALDMML 202
            ||....||..:|.:|:||:...:  .::|..|..||.:..    :|....|||.|...|    :.
  Fly   125 NGHAPAGGCLLATACEYRVMRPN--FLIGLNEAQLGIIAPKWLMSGFASILPKRVAERA----LT 183

Human   203 TGRSIRADRAKKMGLVDQL--------------------VEPLGPGLKPPEERTIEYLEEVAITF 247
            .||......|.::||:|::                    |.||..||...:.|. :.::|..:..
  Fly   184 QGRMFTTQEAFEVGLIDEIASSKEEALEKCAAFIGTFAKVNPLARGLTKLQFRG-DNIKEFEMIR 247

Human   248 AKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRK 292
            .|.:|| .::.....|:.:.:.||           .:.::.||:|
  Fly   248 EKDIAD-FVALASSPGVQKVMGAY-----------LENLKNKVKK 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HADHA	NP_000173.2	fa_ox_alpha_mit	27..762	CDD:131494	72/292 (25%)
CG4594	NP_609323.1	crotonase-like	35..280	CDD:474030	65/269 (24%)