Protein Alignment ihhb and hh

DIOPT Version :9

• Sequence 1: NP_571163.1
• Gene: ihhb / 30299
• ZFINID: ZDB-GENE-980526-135
• Length: 412
• Species: Danio rerio
• Sequence 2: NP_001034065.1
• Gene: hh / 42737
• FlyBaseID: FBgn0004644
• Length: 471
• Species: Drosophila melanogaster
• Alignment Length: 423
• Identity: 187/423 - (44%)
• Similarity: 258/423 - (60%)
• Gaps: 36/423 - (8%)

Zfish     2 RLSTAAALLTGFI-LAFSPAYDGCGPGRGYGKRRTPRKLTPLAYKQFSPNVAEKTLGASGRYEGK 65
            ||::..|||...: :.||||: .||||||.|:.|. |.|.||..||..||::|.|..|||..||.
  Fly    63 RLTSLVALLLIVLPMVFSPAH-SCGPGRGLGRHRA-RNLYPLVLKQTIPNLSEYTNSASGPLEGV 125

Zfish    66 VTPSSERFKELTPNYNPDIIFKDEENTGADRMMTQRCKDKLNSLAISVMNLWPGVRLRVTEGWDE 130
            :...|.:||:|.||||.||:|:|||.|||||:|::|||:|||.||.||||.|||:||.|||.|||
  Fly   126 IRRDSPKFKDLVPNYNRDILFRDEEGTGADRLMSKRCKEKLNVLAYSVMNEWPGIRLLVTESWDE 190

Zfish   131 DGLHSEESLHYEGRAVDITTSDRDRNKYRMLARLAVEAGFDWVYYESKGHVHCSVKSEHSVAAKT 195
            |..|.:||||||||||.|.|||||::||.||||||||||||||.|.|:.|::|||||:.|:::..
  Fly   191 DYHHGQESLHYEGRAVTIATSDRDQSKYGMLARLAVEAGFDWVSYVSRRHIYCSVKSDSSISSHV 255

Zfish   196 GGCFPGRALVTMKDGSHRQIRDLQAGDLVLASEGSDGTGDLIYSEVLTFLDRRPITQKHFYVIRT 260
            .|||...:...::.|..:.:.:|..||.||:...:   |..:||||:.|:||.....::|..:.|
  Fly   256 HGCFTPESTALLESGVRKPLGELSIGDRVLSMTAN---GQAVYSEVILFMDRNLEQMQNFVQLHT 317

Zfish   261 EDGASVSLTAAHLLFMRVGNCSNRGEPKPGAVRTIFASDAQVGQCLLL-----GKLRKRFSQITH 320
            :.||.:::|.|||:.:        .:|:...:..:||...:....:|:     |:||.:  ::..
  Fly   318 DGGAVLTVTPAHLVSV--------WQPESQKLTFVFADRIEEKNQVLVRDVETGELRPQ--RVVK 372

Zfish   321 VGVREDQGLYPPLTAHGTVVVNDVLTSCYAAVNRQRLAHWAFAPLRL---LYSWTGPDQVL---- 378
            ||....:|:..|||..||:|||.|..||||.:|.|.||||..||:||   |.:|....:.|
  Fly   373 VGSVRSKGVVAPLTREGTIVVNSVAASCYAVINSQSLAHWGLAPMRLLSTLEAWLPAKEQLHSSP 437

Zfish   379 --------KNGLHWYSQVLIGLGKLLLDSELFH 403
                    :||:|||:..|..:...:|.....|
  Fly   438 KVVSSAQQQNGIHWYANALYKVKDYVLPQSWRH 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ihhb	NP_571163.1	HH_signal	39..184	CDD:279432	94/144 (65%)
		Hint	187..398	CDD:279426	69/230 (30%)
		Hint	198..348	CDD:238035	43/154 (28%)
hh	NP_001034065.1	HH_signal	99..243	CDD:279432	94/143 (66%)
		Hint	254..465	CDD:279426	67/223 (30%)
		Hint	258..400	CDD:238035	43/154 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573905
Domainoid	1	1.000	230	1.000	Domainoid score	I2380
eggNOG	1	0.900	-	-		E1_KOG3638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	367	1.000	Inparanoid score	I2110
OMA	1	1.010	-	-		QHG50028
OrthoDB	1	1.010	-	-		D1169356at2759
OrthoFinder	1	1.000	-	-		FOG0001612
OrthoInspector	1	1.000	-	-		otm25233
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11889
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1177
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.870