DRSC/TRiP Functional Genomics Resources

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Protein Alignment her6 and E(spl)m8-HLH

DIOPT Version :9

Sequence 1:NP_571154.2 Gene:her6 / 30288 ZFINID:ZDB-GENE-980526-144 Length:270 Species:Danio rerio
Sequence 2:NP_524513.1 Gene:E(spl)m8-HLH / 43161 FlyBaseID:FBgn0000591 Length:179 Species:Drosophila melanogaster


Alignment Length:237 Identity:49/237 - (20%)
Similarity:94/237 - (39%) Gaps:67/237 - (28%)


- Green bases have known domain annotations that are detailed below.


Zfish    34 HRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNMQRAQMTA 98
            ::|..||::|::||||:|:.|..||||:.:....|..  .:::||::||..|..:| .|:.....
  Fly    10 YQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGI--LRMDKAEMLESAVIFMR-QQKTPKKV 71

Zfish    99 ALNTDPTVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLASCMTQINAMNYPTQHQIPA 163
            |.......|..::.|:...:|||:|.:::..|::.::...::.||......:.            
  Fly    72 AQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQ------------ 124

Zfish   164 GPPHPSFSQPMVQIPSATQQANVVPLSGVPCKSGSSSNLTSDATKVYGGFQLVPATDGQFAFLIP 228
                        |...|...|:.:. :.:.|.|...:.|:             ||:.|       
  Fly   125 ------------QFHEAQSAADFIQ-NSMDCSSMDKAPLS-------------PASSG------- 156

Zfish   229 NAAFAPNGPVIPVYANNSNTPVPVAVSPGAPSVTSDSVWRPW 270
                         |.::.::|.|      :|......:||||
  Fly   157 -------------YHSDCDSPAP------SPQPMQQPLWRPW 179

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
her6NP_571154.2 HLH 32..95 CDD:238036 22/60 (37%)
Hairy_orange 110..148 CDD:284859 8/37 (22%)
E(spl)m8-HLHNP_524513.1 HLH 10..67 CDD:238036 22/59 (37%)
ORANGE 81..125 CDD:128787 8/67 (12%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170573735
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4304
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000785
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10985
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
65.840

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