Protein Alignment her6 and E(spl)m8-HLH

DIOPT Version :10

• Sequence 1: NP_571154.2
• Gene: her6 / 30288
• ZFINID: ZDB-GENE-980526-144
• Length: 270
• Species: Danio rerio
• Sequence 2: NP_524513.1
• Gene: E(spl)m8-HLH / 43161
• FlyBaseID: FBgn0000591
• Length: 179
• Species: Drosophila melanogaster
• Alignment Length: 237
• Identity: 49/237 - (20%)
• Similarity: 94/237 - (39%)
• Gaps: 67/237 - (28%)

Zfish    34 HRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNMQRAQMTA 98
            ::|..||::|::||||:|:.|..||||:.:....|..  .:::||::||..|..:| .|:.....
  Fly    10 YQKVKKPMLERQRRARMNKCLDNLKTLVAELRGDDGI--LRMDKAEMLESAVIFMR-QQKTPKKV 71

Zfish    99 ALNTDPTVLGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHLASCMTQINAMNYPTQHQIPA 163
            |.......|..::.|:...:|||:|.:::..|::.::...::.||......:.
  Fly    72 AQEEQSLPLDSFKNGYMNAVNEVSRVMASTPGMSVDLGKSVMTHLGRVYKNLQ------------ 124

Zfish   164 GPPHPSFSQPMVQIPSATQQANVVPLSGVPCKSGSSSNLTSDATKVYGGFQLVPATDGQFAFLIP 228
                        |...|...|:.:. :.:.|.|...:.|:             ||:.|
  Fly   125 ------------QFHEAQSAADFIQ-NSMDCSSMDKAPLS-------------PASSG------- 156

Zfish   229 NAAFAPNGPVIPVYANNSNTPVPVAVSPGAPSVTSDSVWRPW 270
                         |.::.::|.|      :|......:||||
  Fly   157 -------------YHSDCDSPAP------SPQPMQQPLWRPW 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
her6	NP_571154.2	bHLH-O_HES1_4	33..95	CDD:381465	22/60 (37%)
		Hairy_orange	109..148	CDD:462193	8/38 (21%)
E(spl)m8-HLH	NP_524513.1	bHLH-O_ESM5_like	12..70	CDD:381486	22/60 (37%)
		ORANGE	81..125	CDD:128787	8/67 (12%)