DRSC/TRiP Functional Genomics Resources

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Protein Alignment her6 and E(spl)m3-HLH

DIOPT Version :9

Sequence 1:NP_571154.2 Gene:her6 / 30288 ZFINID:ZDB-GENE-980526-144 Length:270 Species:Danio rerio
Sequence 2:NP_524509.2 Gene:E(spl)m3-HLH / 43156 FlyBaseID:FBgn0002609 Length:224 Species:Drosophila melanogaster


Alignment Length:254 Identity:68/254 - (26%)
Similarity:111/254 - (43%) Gaps:55/254 - (21%)


- Green bases have known domain annotations that are detailed below.


Zfish    33 EHRKSSKPIMEKRRRARINESLGQLKTLILDALKKDSSRHSKLEKADILEMTVKHLRNM-QRAQM 96
            ::||..||::|::||||||:.|..||.|:::.|:::....::||||||||:||.|:|.: ||..:
  Fly    10 QYRKVMKPLLERKRRARINKCLDDLKDLMVECLQQEGEHVTRLEKADILELTVDHMRKLKQRGGL 74

Zfish    97 T-----AALNTDPTV-----LGKYRAGFSECMNEVTRFL---STCEGVNTEVRTRLLGHLASCMT 148
            :     |.:.:.||.     :..:|:|:....:::|:.|   ...:.:..::...|...|....|
  Fly    75 SLQGVVAGVGSPPTSTSTAHVESFRSGYVHAADQITQVLLQTQQTDEIGRKIMKFLSTRLIELQT 139

Zfish   149 Q-INAMNYPTQHQIPAGPPHPSFSQPMVQIPSATQQANVVPLSGVPCKSGSSSNLTSDATKVYGG 212
            | :.......|||             ..|||.                  ||..|   |..:.||
  Fly   140 QLLQQQQQQQQHQ-------------QQQIPQ------------------SSGRL---AFPLLGG 170

Zfish   213 FQLVPATDGQFAFLIPNAAF-APNGPVIPVYANNSNTPVPVAVSPGAPSVTSDSVWRPW 270
            :....|     |..|..::| .....:|.|.:.:.|.....|......|..|:.|||||
  Fly   171 YGPAAA-----AAAISYSSFLTSKDELIDVTSVDGNALSETASVSSQESGASEPVWRPW 224

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
her6NP_571154.2 HLH 32..95 CDD:238036 30/62 (48%)
Hairy_orange 110..148 CDD:284859 6/40 (15%)
E(spl)m3-HLHNP_524509.2 HLH 11..70 CDD:238036 28/58 (48%)
ORANGE 96..136 CDD:128787 6/39 (15%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170573732
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4304
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000785
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10985
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
65.840

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