Protein Alignment ndrg3a and MESK2

DIOPT Version :9

• Sequence 1: XP_005169306.1
• Gene: ndrg3a / 30286
• ZFINID: ZDB-GENE-980526-124
• Length: 375
• Species: Danio rerio
• Sequence 2: NP_995914.1
• Gene: MESK2 / 37451
• FlyBaseID: FBgn0043070
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 422
• Identity: 141/422 - (33%)
• Similarity: 200/422 - (47%)
• Gaps: 72/422 - (17%)

Zfish     1 MDELQDVQLTEIKPLLTYKNSQNFQDFDCQEHDIETPHGVLHVTMRGSPKGNRPVILTYHDIGLN 65
            :|.:.|::|..::  |.:.|::......|::..:.|..|.:||.::|...  :|.|:||||:|||
  Fly    20 VDPMDDIELRSVQ--LQFPNARGSILEACEQRRVPTDKGDVHVAIQGDTA--KPAIITYHDLGLN 80

Zfish    66 HKSCFNTLFNFEDMMEITQHFAVVHVDAPGQQEGGPPFPTGYLYPTMDELAEMLPSVLTQLKVNS 130
            :.:.|...|||..|..:.::|.|.||.||||:||.|..|..|:|||||:||..|..||:...:.|
  Fly    81 YATSFAGFFNFPVMRGLLENFCVYHVTAPGQEEGAPTLPEDYVYPTMDDLAAQLLFVLSHFGLKS 145

Zfish   131 VIGIGVGAGAYILTRFALIHPSLVEGLVLINVDPCAEGWIDWAAS-------KLTGWTSNLVDIV 188
            |||.||||||.||.|||..||..|..|.|||......|||:|...       :..|.|..::|.:
  Fly   146 VIGFGVGAGANILARFAHAHPDKVGALCLINCVSTQSGWIEWGYQSFNARFLRTKGMTQGVIDYL 210

Zfish   189 MAHHFSTEELTDNQELIQTYRLHIAQDINQDNLALFCGSYNARQDLGIERPIAGL--NENIVKTL 251
            |.|||.......|.:|:|.|:.|..:.:|..|||:...:|..|.||.:.|...|.  :|....||
  Fly   211 MWHHFGRNPEERNHDLVQMYKQHFERGVNPTNLAMLINAYIHRNDLHLARTPPGTPGSETAATTL 275

Zfish   252 TCPALLVVGDTSPAVEAVVECNSRLNPTKTTLLKMADCGGLPQVVQPGKLAEAFKYFVQGMGYIP 316
            ..|.:.:.|..||.|:..|..|.||:||.::.:|::|| .|....||.||||||:.|:||.||..
  Fly   276 KMPVINITGSLSPHVDDTVTFNGRLDPTNSSWMKISDC-ALVLEEQPAKLAEAFRLFLQGEGYAT 339

Zfish   317 HVLLSHLSCESVPAA------------------------GMTRLSRSR----------------- 340
            .:        |.||:                        .|....|.|
  Fly   340 PL--------STPASSPCGTKYHTYSSIFFANFREQQQQAMEERDRERERERDRQRQLSLRVGNR 396

Zfish   341 ---------SSSSSITSTDGSRNRNLNSPLDG 363
                     ||:|:.|:..|..|......:||
  Fly   397 LRETAINCTSSNSNTTAGQGDNNNADGRSVDG 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ndrg3a	XP_005169306.1	Ndr	31..316	CDD:251726	121/293 (41%)
MESK2	NP_995914.1	Abhydrolase	51..337	CDD:304388	119/288 (41%)
		MhpC	57..334	CDD:223669	115/279 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595952
Domainoid	1	1.000	228	1.000	Domainoid score	I2419
eggNOG	1	0.900	-	-		E1_KOG2931
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40903
Inparanoid	1	1.050	236	1.000	Inparanoid score	I3357
OMA	1	1.010	-	-		QHG55737
OrthoDB	1	1.010	-	-		D359278at33208
OrthoFinder	1	1.000	-	-		FOG0000626
OrthoInspector	1	1.000	-	-		otm24967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11034
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X370
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.910