DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wnt11 and Wnt6

DIOPT Version :9

Sequence 1:	NP_571151.1	Gene:	wnt11 / 30283	ZFINID:	ZDB-GENE-980526-249	Length:	352	Species:	Danio rerio
Sequence 2:	NP_001260188.1	Gene:	Wnt6 / 34010	FlyBaseID:	FBgn0031902	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	422	Identity:	131/422 - (31%)
Similarity:	194/422 - (45%)	Gaps:	104/422 - (24%)

- Green bases have known domain annotations that are detailed below.

Zfish    10 LCLLTFLLLSQQCTGIRWLALSQTAQHINKTQHCKTLPGLVSSQAQLCRSNLELMQTII-----Q 69
            |.::..|:.:...||..|  ...|...::....||....|....|::||.:..|::.||     .
  Fly     4 LMVIAILIFAMPMTGFGW--AEGTNILLDPNLMCKKTRRLRGKLAEICRHDSALLKEIIINGINL 66

Zfish    70 AAREVKKVCQKTFTDMRWNCSSIDGPKFLPDLERGTRESAFVYALSAAAISHTIARACTSGDLRL 134
            ..||    |:..|.:.||||:.: .......|.|.:||:.||.|::||.:::.:.:|||.|.|..
  Fly    67 GFRE----CEFQFRNRRWNCTVL-RKSMRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVE 126

Zfish   135 CSC------------------------------------------------------------GP 139
            |||                                                            .|
  Fly   127 CSCDKAHMRRNGGQPQMVTAATAEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIAP 191

Zfish   140 I---------PG------------EIPEPGYRWGGCADNIHYGLLMGSKFSDAPMKMKKKSGSHA 183
            :         ||            :.||..:.||||:||:::||.....|.||..:.::   |..
  Fly   192 VEHRGGRNRRPGGRRGRRKFWDNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRR---SDL 253

Zfish   184 NKLMHLHNSEVGRQALRDALVMKCKCHGVSGSCSIRTCWRGLLDLKDIAIDLKTKYLSATKVVHR 248
            ..|:..||:..||.|:|||:.::|||||:||||:::|||..:...:::|..|:.:|.||.||..|
  Fly   254 GTLVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKVTLR 318

Zfish   249 PMGTRKQLVPKDIDIRPVRENELVYLQSSPDYCMKNDKLGSFGTQDRQCNKTSSGSDSCDLMCCG 313
            ..|  ...:|:....||..:.:||:...|||:|..|.|.|:.|||.|:||.||||||.||.:||.
  Fly   319 NDG--NSFMPESPHARPANKYQLVFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCN 381

Zfish   314 RGYNPYTERVVE---RCHCKYHWCCYVTCKKC 342
            ||   :|.|:||   .|.|.:.|||.|||:||
  Fly   382 RG---HTRRIVEEQTNCKCVFKWCCEVTCEKC 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wnt11	NP_571151.1	wnt	49..352	CDD:278536	123/383 (32%)
Wnt6	NP_001260188.1	wnt	41..419	CDD:278536	123/383 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900