Protein Alignment jak1 and Src42A

DIOPT Version :9

• Sequence 1: NP_571148.1
• Gene: jak1 / 30280
• ZFINID: ZDB-GENE-980526-142
• Length: 1153
• Species: Danio rerio
• Sequence 2: NP_610191.2
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1597
• Species: Drosophila melanogaster
• Alignment Length: 483
• Identity: 137/483 - (28%)
• Similarity: 205/483 - (42%)
• Gaps: 143/483 - (29%)

Zfish   688 AWKFQVAKQLASALSYLEDKKMV-----HGYVCSKN--------ILVARDG----------LDGE 729
            :|.|:..|::.:      :||::     ||....::        .|..|||          || |
  Fly  1209 SWYFRKIKRIEA------EKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGDTVKHYRIRQLD-E 1266

Zfish   730 GGPFIKLSDPGIPITVLSREECVDRIPWIAPECVKDTANLSIAADKWSFGTTLWEICYNGEIPLK 794
            ||.||...     .|..:.:|.|:...       ||:..|                |.|
  Fly  1267 GGFFIARR-----TTFRTLQELVEHYS-------KDSDGL----------------CVN------ 1297

Zfish   795 DKKLTEKERFYAAQCQLATPDCDELAKLMTHCMTYDPRQRLFFRAIVRDIVMVEKQNPSIQPVPM 859
                            |..| |.::.|.:|..:::..|.:
  Fly  1298 ----------------LCKP-CVQIEKPVTEGLSHRTRDQ------------------------- 1320

Zfish   860 LEVDPTVFEKRFLKKIRDLGEGHFGKVELCRYDPRGDRTGELVAVKSLKPENREEQSNNLWREIH 924
            .|:|.|     .||.:|.||.|.||.|    ::...:.|.. ||:|:||....:.:  :...|..
  Fly  1321 WEIDRT-----SLKFVRKLGSGQFGDV----WEGLWNNTTP-VAIKTLKSGTMDPK--DFLAEAQ 1373

Zfish   925 ILRELYHENIVKYKGICNEEGGRSIKLIMEFLPAGSLKEYLPR---NKAHINLKTLLNYSVQICQ 986
            |:::|.|..:::...:|..|  ..|.:|.|.:..|||.|||..   ....:.::||::.:.||..
  Fly  1374 IMKKLRHTKLIQLYAVCTVE--EPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAA 1436

Zfish   987 GMDYLGSRNYIHRDLAARNVLVENEGTVKIGDFGLTKSIKDNEGYYTVKDDLDSPVFWYAPECLI 1051
            ||.||.|:||||||||||||||.:...|||.||||.:.||::|  |..:.....|:.|.|||...
  Fly  1437 GMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDE--YEARVGARFPIKWTAPEAAN 1499

Zfish  1052 HCKFYRASDVWSFGVTMYELLTYCDASCSPMSVFLKLIG--PTHGQMTVTRLVKVLEEGKRLPRP 1114
            :.||...|||||||:.:.||:||               |  |..| ||...::..:|.|.|:|:|
  Fly  1500 YSKFSIKSDVWSFGILLTELVTY---------------GRIPYPG-MTNAEVLTQVEHGYRMPQP 1548

Zfish  1115 DDCSEQLYNLMRRCWEATPEKRINFKSL 1142
            .:|..:||.:|..||...|.:|..|::|
  Fly  1549 PNCEPRLYEIMLECWHKDPMRRPTFETL 1576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
jak1	NP_571148.1	B41	35..276	CDD:214604
		FERM_C_JAK1	280..422	CDD:275412
		SH2_Jak1	422..523	CDD:198241
		PTK_Jak1_rpt1	580..845	CDD:270662	32/179 (18%)
		Pkinase_Tyr	580..844	CDD:285015	32/178 (18%)
		PKc_like	867..1150	CDD:304357	102/281 (36%)
		Pkinase_Tyr	872..1146	CDD:285015	102/276 (37%)
Src42A	NP_610191.2	SH2_Src_Src42	1210..1301	CDD:198233	27/147 (18%)
		PTKc_Frk_like	1319..1587	CDD:270653	105/315 (33%)
		Pkinase_Tyr	1328..1580	CDD:285015	102/276 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910