Protein Alignment HSD17B10 and YDL114W

DIOPT Version :10

• Sequence 1: NP_004484.1
• Gene: HSD17B10 / 3028
• HGNCID: 4800
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_010169.1
• Gene: YDL114W / 851444
• SGDID: S000002272
• Length: 308
• Species: Saccharomyces cerevisiae
• Alignment Length: 242
• Identity: 66/242 - (27%)
• Similarity: 117/242 - (48%)
• Gaps: 33/242 - (13%)

Human     9 KGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 73
            |...|:||||:||||...|:.|..:....::.|:.:....||.:.  ||..:...|:||..:::.
Yeast    37 KNATALITGGSSGLGFELAKELSRRINKVIVADIQSFPTFAQVEY--NNIFYYQCDITSLDEIKN 99

Human    74 ALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQ 138
            .....:...|.:::.:|.||:|      ::||.:..|.::.::::|:||:|.:.:|...|.:|..
Yeast   100 LKKAIERDHGNINIIINNAGVA------HIKKLEHMTNKEVEQLIDINLIGAYRIISTFAEDMID 158

Human   139 NEPDQGGQRGVIINTASVAAFEGQVGQA---AYSASKGGIVGMTLPIARDLAPI-------GIRV 193
            |      :.|.|||.|||.   |::..|   :|.||||.::|....::|....:       ||:.
Yeast   159 N------REGFIINIASVL---GELTPARLTSYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKT 214

Human   194 MTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLG----DPAEYAHL 236
            :.:.||...|.:...:|.. ...||..: .||:|.    ...|:.||
Yeast   215 LLVCPGKIKTNMFIDVPTP-SKLLAPDI-IPSQLALAIISAMEHNHL 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B10	NP_004484.1	HSD10-like_SDR_c	9..261	CDD:187629	66/242 (27%)
YDL114W	NP_010169.1	17beta-HSDXI-like_SDR_c	40..282	CDD:187598	65/239 (27%)