Protein Alignment HSD17B10 and Adh

DIOPT Version :10

• Sequence 1: NP_004484.1
• Gene: HSD17B10 / 3028
• HGNCID: 4800
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_001027266.1
• Gene: Adh / 3771877
• FlyBaseID: FBgn0000055
• Length: 256
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 73/259 - (28%)
• Similarity: 109/259 - (42%)
• Gaps: 48/259 - (18%)

Human    14 VITGGASGLGLATAERLVGQG-ASAVLLD-LPNSGGEAQAKKLGN--NCVFAPADVT-----SEK 69
            :...|..|:||.|::.|:.:. .:.|:|| :.|....|:.|.:..  ...|.|.|||     :.|
  Fly    11 IFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPYDVTVPIAETTK 75

Human    70 DVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQ--RVLDVNLMGTFNVIRLV 132
            .::|..|..|    .|||.:|.|||                |:|.|  |.:.||..|..|....:
  Fly    76 LLKTIFAQLK----TVDVLINGAGI----------------LDDHQIERTIAVNYTGLVNTTTAI 120

Human   133 AGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPI-GIRVMTI 196
            .....:.   :||..|:|.|..||..|........||.:|..:|..|..:|: |||| |:...|:
  Fly   121 LDFWDKR---KGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFTSSLAK-LAPITGVTAYTV 181

Human   197 APGLFGTPLL------TSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLD 254
            .||:..|.|:      ..:..:|...|.:....||.    |...:.|:||..|.  ||.:.:||
  Fly   182 NPGITRTTLVHTFNSWLDVEPQVAEKLLAHPTQPSL----ACAENFVKAIELNQ--NGAIWKLD 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B10	NP_004484.1	HSD10-like_SDR_c	9..261	CDD:187629	73/259 (28%)
Adh	NP_001027266.1	ADH_SDR_c_like	8..247	CDD:187584	73/259 (28%)