Protein Alignment HSD17B10 and Fbp2

DIOPT Version :10

• Sequence 1: NP_004484.1
• Gene: HSD17B10 / 3028
• HGNCID: 4800
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_523522.1
• Gene: Fbp2 / 34259
• FlyBaseID: FBgn0000640
• Length: 256
• Species: Drosophila melanogaster
• Alignment Length: 217
• Identity: 45/217 - (20%)
• Similarity: 85/217 - (39%)
• Gaps: 37/217 - (17%)

Human    10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSG-----------GEAQAKKLGNNCVFAPA 63
            |...|..|..||:|.....:|:.:       |:...|           .:.||.......||...
  Fly     6 GKNVVYVGSFSGIGWQMMMQLMQK-------DIKMMGIMHRMENVKMMKKLQAINPSVKVVFMQM 63

Human    64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNV 128
            ::..:..::.|:.......|.:||.:|..|:.:.              :|.:..:.:||.|   :
  Fly    64 NLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLD--------------KDVETTMGMNLTG---M 111

Human   129 IRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDL--APIGI 191
            |:.....|...:..|.|..|:::|.:||...|.....:.|:|:..||:|.|..:...:  ...|:
  Fly   112 IQSTMMAMPYMDKTQMGMGGMVVNMSSVYGLEPAPAFSVYAAAMHGILGFTRSMGDKMIYQKTGV 176

Human   192 RVMTIAPGLFGTPLLTSLPEKV 213
            ..|.:.|||..:.::.:|.:.|
  Fly   177 MFMAMCPGLTNSEMIMNLRDNV 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B10	NP_004484.1	HSD10-like_SDR_c	9..261	CDD:187629	45/217 (21%)
Fbp2	NP_523522.1	ADH_SDR_c_like	7..249	CDD:187584	44/216 (20%)