Protein Alignment HSD17B10 and ayr2

DIOPT Version :10

• Sequence 1: NP_004484.1
• Gene: HSD17B10 / 3028
• HGNCID: 4800
• Length: 261
• Species: Homo sapiens
• Sequence 2: NP_592780.1
• Gene: ayr2 / 2543330
• PomBaseID: SPAC977.08
• Length: 236
• Species: Schizosaccharomyces pombe
• Alignment Length: 196
• Identity: 47/196 - (23%)
• Similarity: 80/196 - (40%)
• Gaps: 31/196 - (15%)

Human    51 AKKLG--NNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLED 113
            ||.|.  .|.:....||.:...::.::..|...|||:||.:|.||.:|.|..      ::.|.|.
pombe     7 AKVLSRLENVLVTQLDVNNFSSIKKSVEKAISHFGRIDVLLNNAGYSVYSPL------ESTTEEQ 65

Human   114 FQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178
            ...:.:.|:.|...||:.:....      :....|:|||.:|:...........|..:|..|.|:
pombe    66 IHNIFNTNVFGALEVIKAITPIF------RSQHNGMIINVSSIGGKMTFPLGCLYYGTKYAIEGI 124

Human   179 TLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDP-AEYAHLVQAIIE 242
            :..:..::..||::|..|.||                |.|::.......|.. |||.:|.|.:.|
pombe   125 SEALTWEMQSIGVKVKIIEPG----------------FTATEFRVEEGAGKHYAEYDNLKQKLYE 173

Human   243 N 243
            :
pombe   174 D 174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B10	NP_004484.1	HSD10-like_SDR_c	9..261	CDD:187629	47/196 (24%)
ayr2	NP_592780.1	Rossmann-fold NAD(P)(+)-binding proteins	11..210	CDD:473865	44/192 (23%)