Protein Alignment sema3aa and Sema1b

DIOPT Version :9

• Sequence 1: NP_571135.1
• Gene: sema3aa / 30266
• ZFINID: ZDB-GENE-991209-3
• Length: 860
• Species: Danio rerio
• Sequence 2: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Alignment Length: 586
• Identity: 183/586 - (31%)
• Similarity: 285/586 - (48%)
• Gaps: 58/586 - (9%)

Zfish    45 LVTFTGLANSSGYDTFLMDGERGRLLVGAEDHVFSFDLVNINRDVKQIAWPATPSKRDECKWAGK 109
            |..|.|  ||:.|.. ::|.....:||||:|.:::..| |..:::.::.|.:|.:.|:.|...||
  Fly    50 LAHFIG--NSTDYFK-ILDHNDEFVLVGAKDVIYNVSL-NGLKEIARLEWHSTDADRELCALKGK 110

Zfish   110 DLRKDCSNFVRVLQSYNQTHIYICGTGAFHPIC--------SFLEMGKRAEDNIFRLDANYFENG 166
            . ..||.|::||........:.:|||.::.|.|        |..|.|.....:..|.:.:.....
  Fly   111 H-EWDCHNYLRVYALRPNGEVLLCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEA 174

Zfish   167 RGKSPYDPKMQSSSLLLDGELYSGTSADFMGRDFAIFRTLGSHHPIRTEQHDSRWLNEPRFLGIH 231
            :|..||.|...|:....||.|||.|.|||.|.|..|:|     ..:||||:|.:.||:|.|:|.
  Fly   175 QGLCPYSPAHNSTYAFADGHLYSATVADFSGGDPLIYR-----ENLRTEQYDLKQLNQPDFVGA- 233

Zfish   232 LIPESDNPEDDKIFLFFKENAMDGEHTGKATISRIGQLCKNDMGGHRSLVNKWTTFLKAKLTCSV 296
                  ...:..:..||:|.:|:..:.|||..||:.::||||.||..|....||:||||:|.|||
  Fly   234 ------IERNGYVLFFFRELSMEVMNFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSV 292

Zfish   297 PGLNGIDTHFDELQDVFLMSAKDPKNPVIYAVFTTSSNIFRGSAICMYSMADIRRVFLGPYAHRD 361
            ||  ....:|||:|.:..:.....|: :||||||||.|...|||:|.:::.||...|.|.:..:.
  Fly   293 PG--EFPFYFDEIQAISPIVESGSKS-LIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQK 354

Zfish   362 GPNYQWVPFQ-GRVPYPRPGTCPSKTFGGFDSTKDLPDDVITFARLHPAMYNPVQPMGGKPIVVR 425
            .....|:|.: .:||.||||.|       .:.::.|....:.|.:.||.|...|..:.|:|::.:
  Fly   355 DSQSHWLPVEREQVPKPRPGQC-------VEDSRTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTK 412

Zfish   426 TNVEYQFTQLVV-DRVEAEDG-QYDVMFIGTDLGTVLKVVTI----PRESWHDLEEVVLEEMTVF 484
            .|:.::.|.:.| .:|::..| .|||::.|||.|.|.|.:.|    |..:...|:.||:.||.|.
  Fly   413 VNLHHRLTAIAVHPQVKSLSGAYYDVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVL 477

Zfish   485 REPTPITAMELSTKQQQLYLGSDLGISQMPLHRCEVYGKACAECCLARDPYCAWD--GTECSRYF 547
            ...|||..:.:||.:..|.:.||..:..:|||.|. :...|..|...:||.||||  ..||....
  Fly   478 PLGTPIRELVISTSKNSLVVVSDGSLVSVPLHHCS-HIVDCLGCLSLQDPICAWDLQTHECKNLA 541

Zfish   548 PTAKR---RTRRQDIRNGDPLSQCSDLHHNDDLEGYSSVEERSVYGVENSSMFLECSPKSQRALI 609
            .:..:   :|..|.:.:....:.....|...|..|..:|          |.:.:...|..::.|:
  Fly   542 TSQHKFGTKTYLQSLNSTKKAAALLCPHIPRDAPGAETV----------SFVTMAPPPTEEQKLL 596

Zfish   610 Y 610
            |
  Fly   597 Y 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sema3aa	NP_571135.1	Sema	26..519	CDD:301699	162/488 (33%)
		PSI	517..569	CDD:214655	13/56 (23%)
		Ig_Semaphorin_classIII	583..673	CDD:143279	5/28 (18%)
		IG_like	586..654	CDD:214653	4/25 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	725..860
		DUF4887	<744..859	CDD:292845
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	160/482 (33%)
		PSI	510..>537	CDD:214655	9/27 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910