DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tbx16 and byn

DIOPT Version :9

Sequence 1:	NP_571133.1	Gene:	tbx16 / 30264	ZFINID:	ZDB-GENE-990615-5	Length:	470	Species:	Danio rerio
Sequence 2:	NP_524031.2	Gene:	byn / 39349	FlyBaseID:	FBgn0011723	Length:	697	Species:	Drosophila melanogaster

Alignment Length:	517	Identity:	157/517 - (30%)
Similarity:	226/517 - (43%)	Gaps:	154/517 - (29%)

- Green bases have known domain annotations that are detailed below.

Zfish    21 GAGDSYH-QGNIRMTLEDPELWRSFHEIGTEMIITKPGRRMFPHCKISLSGLVPYAKYILLVDMV 84
            |||.... ..|:|::|:|.|||..|..:..|||:||.||||||..|||.|||.|.|.|.:|::.|
  Fly    76 GAGSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFV 140

Zfish    85 PEDGLRYKWNKDKWEVAGKAEPQPPYRTYLHPDSPAPGSHWMKQPVSFLKLKLTNNALDQHGHII 149
            ..|..|:|:...:|...||||..|....|:||:||..|:||||:|:||.|:||||.. :.:|.|:
  Fly   141 QIDSHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNKT-NGNGQIM 204

Zfish   150 LHSMHRYHPRFHIVQ--ADDLYSVRWSVFQTFTFPETSFTAVTAYQNTKITKLKIDHNPFAKGFR 212
            |:|:|:|.||.|:|:  ::..:.|      |:.||||.|.|||||||.::|.|||.:|||||.|.
  Fly   205 LNSLHKYEPRVHLVRVGSEQRHVV------TYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFL 263

Zfish   213 DEGTNSKRRANR----------NLPDPER---------VAKKMSKDSEHG---------SPQDVQ 249
            |    :|.|.:.          .:|.|..         ....:|....||         |.:.|.
  Fly   264 D----AKERPDTLYPHDTHYGWLIPPPTHYTAAAAAVAAPPPLSIAQSHGLVASCPSVSSAESVG 324

Zfish   250 PSSCEALDDEHAGRKELEVKAERYSPWGGACDRDSGHALRPESPLGSDHRDVYSSEQLVPGQNTY 314
            |||                        ||:||| .|.:|              ||..:.|.:.|
  Fly   325 PSS------------------------GGSCDR-YGRSL--------------SSRSVAPTRTT- 349

Zfish   315 QPYRFHEYGKSPSPSSSSSVGGSSACGSAGRPSFESRVLDVATVPDTDSSSKPSSAPEFSLPPHP 379
             ||           |....|.||.:.||||..|              .:|.:|.|||:     .|
  Fly   350 -PY-----------SRPRVVSGSGSNGSAGNAS--------------STSPQPPSAPQ-----TP 383

Zfish   380 SAGHQEYAGVLNMAITQAKPGMLGTHP------------------------LYSHYSTEQSLGQW 420
            ::.|....|.::.:::.:..|.:|:.|                        ::|:.|:.||.|.:
  Fly   384 TSLHSTSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSNGNY 448

Zfish   421 SGAAASQYPPP--------------PPPHHHLP---TEYSSQAVHHGYHHGNVGDWSQYPLF 465
            ..|.:...|.|              |.|.:..|   |...|..:||...|.:..:.:|..::
  Fly   449 WNATSVPGPMPMNVCSGRNISSHNSPSPTNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIY 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbx16	NP_571133.1	TBOX	30..217	CDD:238106	92/188 (49%)
byn	NP_524031.2	TBOX	86..268	CDD:238106	93/192 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810