Protein Alignment tbx2b and Doc1

DIOPT Version :9

• Sequence 1: NP_571126.1
• Gene: tbx2b / 30253
• ZFINID: ZDB-GENE-990726-27
• Length: 687
• Species: Danio rerio
• Sequence 2: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Alignment Length: 525
• Identity: 164/525 - (31%)
• Similarity: 231/525 - (44%)
• Gaps: 187/525 - (35%)

Zfish    73 HQAAHLRSLKSLEPEEEVEDDPKVTLEAKDLWDQFHKLGTEMVITKSGRRMFPPFKVRINGLDKK 137
            ||..|:     :.|........:..||..|||.||||:||||:||||||||||..:|.::||:::
  Fly    43 HQQPHM-----MLPSRPTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEE 102

Zfish   138 AKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTN 202
            |.|.:|:::|...||||||..|:|:.||.|:|:.|:|||:||||||||..|.::.:.|:|:||||
  Fly   103 ASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTN 167

Zfish   203 NISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKITQLKIDN 267
            |..|..|..:|.||||||||.||:|::::.:||::..:.:|||||:|:||||||||:||:|||||
  Fly   168 NTLDSSGHIVLASMHKYQPRLHIIRSSELTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDN 232

Zfish   268 NPFAKGFRDTGNGRREKRKQLTLPSLRMYEDQCKVDRDGADSDASSSEPTTGRDAGHSPGPVSSP 332
            ||||||||::|..|                  ||...:.:.:....||
  Fly   233 NPFAKGFRESGQSR------------------CKRKLNSSGNSTLESE----------------- 262

Zfish   333 LRFNRGSRDDKTCTDSEHEMDHQNDRCGGSSSPAPKPSSPFRSRSEDWGREKPIAEKKDDYPDSR 397
                    ||                 |.|.|....|.:
  Fly   263 --------DD-----------------GSSVSSCDSPQA-------------------------- 276

Zfish   398 KTSDSIFSIRNLEKDKLESRSRKDTDSSKKDTENSGISGSKDSFSPLMVQTESPSHFGAGHLQSL 462
                              .|.|:|.:.     :::|              :.||:::||.|
  Fly   277 ------------------KRQRQDFEQ-----DSTG--------------SVSPAYYGATH---- 300

Zfish   463 ALSGLHSQQFFNPLNTGQPLLFHPGQFAMAPGAFSAMGMGHLLASVSGAGGLENGSLSAQGTGST 527
                    ...||::   |.|.|                 ||....|||.||. .|::|...|..
  Fly   301 --------PVANPMS---PYLRH-----------------HLSYGPSGAAGLP-PSIAAAYFGGV 336

Zfish   528 PSPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPASSST-------ASSLSRNP 585
            |             .|.:|||      |..|....|..:..::.|..|||       ::|..||.
  Fly   337 P-------------PQILPMP------PATYAPTVAPVSPVASQPVGSSTPTTSPRPSTSTKRNS 382

Zfish   586 FLSSS 590
            |..|:
  Fly   383 FSISA 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbx2b	NP_571126.1	TBOX	95..278	CDD:238106	107/182 (59%)
		TBX	294..361	CDD:204975	6/66 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..452		13/148 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	611..687
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	108/186 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840