Protein Alignment tbx2b and org-1

DIOPT Version :9

• Sequence 1: NP_571126.1
• Gene: tbx2b / 30253
• ZFINID: ZDB-GENE-990726-27
• Length: 687
• Species: Danio rerio
• Sequence 2: NP_001285019.1
• Gene: org-1 / 31778
• FlyBaseID: FBgn0021767
• Length: 699
• Species: Drosophila melanogaster
• Alignment Length: 586
• Identity: 189/586 - (32%)
• Similarity: 263/586 - (44%)
• Gaps: 161/586 - (27%)

Zfish    55 HTLAGAAEAGLHPALSHHHQAAHLRSLKSLEPEEEVEDDPKVTLEAKDLWDQFHKLGTEMVITKS 119
            |.::......:||:|:   ||.                   |.||.|.||||||..||||:|||:
  Fly   179 HNISKGESEPVHPSLA---QAI-------------------VVLETKALWDQFHAQGTEMIITKT 221

Zfish   120 GRRMFPPFKVRINGLDKKAKYILLMDIVAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSP 182
            ||||||.|:|||.|||..|.||.:||.|..||.||:  ||||.|:|||||||..|.|:::|||||
  Fly   222 GRRMFPTFQVRIGGLDPHATYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSP 286

Zfish   183 ATGEQWMAKPVAFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLP-----------Y 236
            |.|..||.:.|:|.|||||||..|::|..||||||:||||||:|      .||           .
  Fly   287 AVGSNWMKQIVSFDKLKLTNNQLDENGHIILNSMHRYQPRFHLV------YLPPKNASLDENEHS 345

Zfish   237 STFRTYVFPETDFIAVTAYQNDKITQLKIDNNPFAKGFRD-------TGNG-------------- 280
            |.|||::||||.|.|||||||.::|||||.:|||||||||       ||.|
  Fly   346 SHFRTFIFPETSFTAVTAYQNQRVTQLKISSNPFAKGFRDDGTNDVTTGGGSSMSSMSHESQARM 410

Zfish   281 ----RREKRKQLTLPSLRMYEDQCKVDRDGADSDASSSEPTTGRDAGHSPGPVSSPLRFNRGSRD 341
                ::::::|..|...:..:.|.| :|..|.|:...|
  Fly   411 KQQQQQQQQQQQQLQQQQQQQQQLK-ERTAATSNFGLS--------------------------- 447

Zfish   342 DKTCTD-SEHEMDHQNDRCGGSSSPAPKPSSPFRSRSED---WGREKPIAEKKDDYPDSRKTSDS 402
               |:: :..:...|..:.|....||...||.....|.|   :..|:.:.::.......:..|
  Fly   448 ---CSELAIEQQQQQQQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQQLQQQHQQQQQQQHQS-- 507

Zfish   403 IFSIRNLEKDKLESRSRKDTDSSKKDTENSGISGSKDSFSPLMVQTESPSHFGAGHLQSLALSGL 467
                   ::..|..:.:.:...|                  |:.|:::.:.:|:.|
  Fly   508 -------QQQHLHQQHQANQQQS------------------LLQQSQNHTQYGSYH--------- 538

Zfish   468 HSQQFFNPLNTGQPLLFHPGQFAMAPGAFSAMGMGHLLASVSGAGGLENGSLSAQGTGSTPSPFP 532
            |:.|   ......||..|....| :|.|.:|.|.....|:|:|..|       |.|.|...|...
  Fly   539 HAYQ---AQVQSHPLTPHSSSSA-SPPATAAPGASAATAAVAGGAG-------AAGAGGATSATQ 592

Zfish   533 FHLSQHMLASQGIP----MPTFGGLFPYPYTYMAAAAAAA-----SALPASSSTASSLSRNPFLS 588
            ...:.::.:|.|.|    ...||.:    |.:.|||||||     .|...:.|.|.:.:..|:.|
  Fly   593 VMSAANIYSSIGQPYAQEQSNFGAI----YHHNAAAAAAAHYHHGHAHGHAHSHAHAHAHGPYAS 653

Zfish   589 S 589
            :
  Fly   654 A 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbx2b	NP_571126.1	TBOX	95..278	CDD:238106	119/202 (59%)
		TBX	294..361	CDD:204975	8/67 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..452		19/152 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	611..687
org-1	NP_001285019.1	TBOX	195..389	CDD:238106	121/218 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840