DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment neurog1 and twi

DIOPT Version :9

Sequence 1:	NP_571116.1	Gene:	neurog1 / 30239	ZFINID:	ZDB-GENE-990415-174	Length:	208	Species:	Danio rerio
Sequence 2:	NP_001033967.1	Gene:	twi / 37655	FlyBaseID:	FBgn0003900	Length:	490	Species:	Drosophila melanogaster

Alignment Length:	189	Identity:	52/189 - (27%)
Similarity:	79/189 - (41%)	Gaps:	31/189 - (16%)

- Green bases have known domain annotations that are detailed below.

Zfish    16 SFSHTDDEDSRSSLHPA-SPASSCGKPPASPAGLQ-------------------QKKRRRGRARN 60
            ::|.:|.:|...:.|.| |..|.......|||.|.                   :|.|||.:.:.
  Fly   287 AYSSSDRDDMEYARHNALSSVSDLNGGVMSPACLADDGSAGSLLDGSDAGGKAFRKPRRRLKRKP 351

Zfish    61 ETTVHVVK-KNRRLKANDRERNRMHNLNDALDALRSVLPAFPDDTKLTKIETLRFAHNYIWALSE 124
            ..|....: .|:|:.||.|||.|..:||||..:|:.::|..|.| ||:||:||:.|..||..|..
  Fly   352 SKTEETDEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSD-KLSKIQTLKLATRYIDFLCR 415

Zfish   125 TIRIADQKQGKSRDGPLLLPGLSCMADAPSPGSDSCSWPSGASSSSSSPSYCNSDPGSP 183
            .:..:|..         ||..|.......:.||.|....:.|:.:.:.........|:|
  Fly   416 MLSSSDIS---------LLKALEAQGSPSAYGSASSLLSAAANGAEADLKCLRKANGAP 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
neurog1	NP_571116.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..62		15/65 (23%)
		CCDC106	<20..>102	CDD:292422	29/102 (28%)
		HLH	68..127	CDD:238036	26/59 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	159..180		2/20 (10%)
twi	NP_001033967.1	HLH	363..413	CDD:278439	24/50 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910